Concordance between cerebrospinal fluid biomarkers and [11C] PIB PET in a memory clinic cohort

M Zwan, A van Harten, R Ossenkoppele… - Journal of …, 2014 - content.iospress.com
Background: Two approaches are available for measuring Alzheimer's disease (AD)
pathology in vivo. Biomarkers in cerebrospinal fluid (CSF) include amyloid-β 1-42 (Aβ 42) …

Serum fragments of Tau for the differential diagnosis of Alzheimer's disease

D Inekci, K Henriksen, T Linemann… - Current alzheimer …, 2015 - ingentaconnect.com
Differential diagnosis of AD is still a challenge due to overlapping features with other types
of dementia. Biomarkers for the differential diagnosis of AD can improve the diagnostic value …

Comparison of diagnostic performances between cerebrospinal fluid biomarkers and amyloid PET in a clinical setting

NY Jung, ES Kim, HS Kim, S Jeon… - Journal of …, 2020 - content.iospress.com
The diagnostic performances of cerebrospinal fluid (CSF) biomarkers and amyloid positron
emission tomography (PET) were compared by examining the association and concordance …

Amyloid β (Aβ) and phospho-tau (p-tau) as diagnostic biomarkers in Alzheimer's disease

D Prvulovic, H Hampel - Clinical chemistry and laboratory medicine, 2011 - degruyter.com
A growing body of evidence suggests that Alzheimer's disease (AD) is a multifactorial
disease resulting in the well-known, common neuropathological pathway characterized by …

Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects

JB Pereira, S Janelidze, E Stomrud, S Palmqvist… - Brain, 2021 - academic.oup.com
It is currently unclear whether plasma biomarkers can be used as independent prognostic
tools to predict changes associated with early Alzheimer's disease. In this study, we sought …

Plasma pTau‐217 and N‐terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid‐β positive individuals

MS Woo, C Tissot, J Lantero‐Rodriguez… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION We set out to identify tau PET‐positive (A+ T+) individuals among amyloid‐
beta (Aβ) positive participants using plasma biomarkers. METHODS In this cross‐sectional …

Multisite study of the relationships between antemortem [11C] PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology

R La Joie, N Ayakta, WW Seeley, E Borys… - Alzheimer's & …, 2019 - Elsevier
Introduction We sought to establish the relationships between standard postmortem
measures of AD neuropathology and antemortem [11 C] PIB–positron emission tomography …

[HTML][HTML] Plasma p-tau181 as a promising non-invasive biomarker of Alzheimer's Disease pathology in Subjective Cognitive Decline and Mild Cognitive Impairment

G Giacomucci, S Mazzeo, C Crucitti, A Ingannato… - Journal of the …, 2023 - Elsevier
Introduction The aim of this study is to investigate the role of plasma phosphorylated tau (p-
tau) 181 as a potential biomarker for Alzheimer's Disease (AD) pathology in the early stages …

Plasma and CSF biomarkers in a memory clinic: head‐to‐head comparison of phosphorylated tau immunoassays

NJ Ashton, A Puig‐Pijoan, M Milà‐Alomà… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Direct comparisons of the main blood phosphorylated tau immunoassays in
memory clinic populations are needed to understand possible differences. Methods In the …

Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease

NJ Ashton, AL Benedet, TA Pascoal, TK Karikari… - …, 2022 - thelancet.com
Background Phosphorylated tau (p-tau) epitopes in cerebrospinal fluid (CSF) are accurate
biomarkers for a pathological and clinical diagnosis of Alzheimer's disease (AD) and are …