For several decades, understanding ageing and the processes that limit lifespan have challenged biologists. Thirty years ago, the biology of ageing gained unprecedented …
Each animal species displays a specific life span, rate of aging and pattern of development of age-dependent diseases. The genetic bases of these related features are being studied …
The field of aging is at a precipice. Attention and funding are increasingly focused on this area, and exciting, fundamentally important findings are being reported literally every day …
H Lees, H Walters, LS Cox - Maturitas, 2016 - Elsevier
Human ageing is the gradual decline in organ and tissue function with increasing chronological time, leading eventually to loss of function and death. To study the processes …
AA Cohen, V Legault, T Fülöp - Mechanisms of ageing and development, 2020 - Elsevier
Are diseases caused by aging? What are the mechanisms of aging? Do all species age? These hotly debated questions revolve around a unitary definition of aging. Because we use …
L Partridge, J Thornton, G Bates - … Transactions of the …, 2011 - royalsocietypublishing.org
Thanks to improvements in hygiene and healthcare, human life expectancy in developed countries has been increasing at a steady rate of about 2.5 years per decade since the …
T Flatt, L Partridge - BMC biology, 2018 - Springer
Between the 1930s and 50s, evolutionary biologists developed a successful theory of why organisms age, firmly rooted in population genetic principles. By the 1980s the evolution of …
The 40 th anniversary of Cell coincides with that of the National Institute on Aging (NIA). Indeed, Cell papers on NIA-funded research helped move the field into a genetic and …
HR Warner, F Sierra - Mechanisms of ageing and development, 2003 - Elsevier
During the past ten years considerable progress has been made in discovering genes that regulate longevity by identifying single gene mutations that lead to increased longevity. The …