Childhood adversity and neural development: A systematic review

KA McLaughlin, D Weissman… - Annual review of …, 2019 - annualreviews.org
An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience

KA McLaughlin, MA Sheridan, HK Lambert - Neuroscience & Biobehavioral …, 2014 - Elsevier
A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental …

Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity

KE Smith, SD Pollak - Perspectives on psychological science, 2021 - journals.sagepub.com
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

Distinct associations of deprivation and threat with alterations in brain structure in early childhood

L Machlin, HL Egger, CR Stein, E Navarro… - Journal of the American …, 2023 - Elsevier
Objective The dimensional model of adversity and psychopathology hypothesizes
deprivation and threat impact distinct neurobiological pathways, such as brain structure. This …

A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing

N Tottenham, MA Sheridan - Frontiers in human neuroscience, 2010 - frontiersin.org
A review of the human developmental neuroimaging literature that investigates outcomes
following exposure to psychosocial adversity is presented with a focus on two subcortical …

[HTML][HTML] Meta-analysis of associations between childhood adversity and hippocampus and amygdala volume in non-clinical and general population samples

M Calem, K Bromis, P McGuire, C Morgan… - Neuroimage …, 2017 - Elsevier
Background Studies of psychiatric populations have reported associations between
childhood adversity and volumes of stress-related brain structures. This meta-analysis …

Early adversity and critical periods: neurodevelopmental consequences of violating the expectable environment

CA Nelson, LJ Gabard-Durnam - Trends in neurosciences, 2020 - cell.com
It is now widely recognized that children exposed to adverse life events in the first years of
life are at increased risk for a variety of neural, behavioral, and psychological sequelae. As …

[HTML][HTML] Long-term neural embedding of childhood adversity in a population-representative birth cohort followed for 5 decades

MZ Gehred, AR Knodt, A Ambler, KJ Bourassa… - Biological …, 2021 - Elsevier
Background Childhood adversity has been previously associated with alterations in brain
structure, but heterogeneous designs, methods, and measures have contributed to mixed …

[HTML][HTML] Deprivation and threat as developmental mediators in the relation between early life socioeconomic status and executive functioning outcomes in early …

SC Vogel, RE Perry, A Brandes-Aitken, S Braren… - Developmental …, 2021 - Elsevier
There has been a shift in the study of childhood adversity towards a focus on dimensions of
adversity as opposed to a focus on cumulative risk or specific adversities. The Dimensional …

Childhood violence exposure and social deprivation are linked to adolescent threat and reward neural function

TC Hein, LG Goetschius, VC McLoyd… - Social cognitive and …, 2020 - academic.oup.com
Background Childhood adversity is, unfortunately, highly prevalent and strongly associated
with later psychopathology. Recent theories posit that two dimensions of early adversity …