Aging is a process of progressive change. To develop biological models of aging,
longitudinal datasets with high temporal resolution are needed. Here we report a multi …

Lifespan varies within and across species, but the general principles of its control remain
unclear. Here, we conducted multi-tissue RNA-seq analyses across 41 mammalian species …

Biological aging of human organ systems reflects the interplay of age, chronic disease,
lifestyle and genetic risk. Using longitudinal brain imaging and physiological phenotypes …

By combining transcriptomic data with other data sources, inferences can be made about
functional changes during ageing. Thus, we conducted a meta-analysis on 127 publicly …

Biological aging reflects decline in physiological functions and is an effective indicator of
morbidity and mortality. Numerous epigenetic age calculators are available, however …

Biological age (BA) is a common model to evaluate the function of aging individuals as it
may provide a more accurate measure of the extent of human aging than chronological age …

A confounding aspect of biological ageing is the nature and role of senescent cells. It is
unclear whether the three major types of cellular senescence, namely replicative …

As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …