Sterilizing immunity: understanding COVID-19

I Wahl, H Wardemann - Immunity, 2022 - cell.com
Immune memory develops during primary infections to protect from future exposures to the
same pathogen. Vaccines mimic this response and induce immune memory that protects …

Prior SARS-CoV-2 infection enhances and reshapes spike protein–specific memory induced by vaccination

V Barateau, L Peyrot, C Saade, B Pozzetto… - Science Translational …, 2023 - science.org
The diversity of vaccination modalities and infection history are both variables that have an
impact on the immune memory of individuals vaccinated against SARS-CoV-2. To gain more …

Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity

LB Rodda, PA Morawski, KB Pruner, ML Fahning… - Cell, 2022 - cell.com
Immune memory is tailored by cues that lymphocytes perceive during priming. The severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic created a situation in …

T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals

T Bilich, A Nelde, JS Heitmann, Y Maringer… - Science translational …, 2021 - science.org
Long-term immunological memory to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is crucial for the development of population-level immunity, which is the aim …

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern

RR Goel, MM Painter, SA Apostolidis, D Mathew… - Science, 2021 - science.org
INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA
vaccines are highly effective at preventing infection and especially severe disease …

SARS-CoV-2 infection generates tissue-localized immunological memory in humans

MML Poon, K Rybkina, Y Kato, M Kubota… - Science …, 2021 - science.org
Adaptive immune responses to SARS-CoV-2 infection have been extensively characterized
in blood; however, most functions of protective immunity must be accomplished in tissues …

Durability and cross-reactive immune memory to SARS-CoV-2 in individuals 2 years after recovery from COVID-19: a longitudinal cohort study

L Guo, Q Zhang, X Gu, L Ren, T Huang, Y Li… - The Lancet …, 2024 - thelancet.com
Summary Background SARS-CoV-2-specific adaptive immunity more than 1 year after initial
infection has not been well characterised. The aim of this study was to investigate the …

Cross-reactive memory T cells and herd immunity to SARS-CoV-2

M Lipsitch, YH Grad, A Sette, S Crotty - Nature Reviews Immunology, 2020 - nature.com
Immunity is a multifaceted phenomenon. For T cell-mediated memory responses to SARS-
CoV-2, it is relevant to consider their impact both on COVID-19 disease severity and on viral …

Naturally acquired SARS-CoV-2 immunity persists for up to 11 months following infection

V De Giorgi, KA West, AN Henning… - The Journal of …, 2021 - academic.oup.com
Background Characterizing the kinetics of the antibody response to severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) is of critical importance to developing strategies …

Durability of vaccine-induced and natural immunity against COVID-19: a narrative review

N Pooley, SS Abdool Karim, B Combadière… - Infectious Diseases and …, 2023 - Springer
Vaccines developed against SARS-CoV-2 have proven to be highly effective in preventing
symptomatic infection. Similarly, prior infection with SARS-CoV-2 has been shown to provide …