People exposed to adverse childhood experiences (ACEs) suffer from an increased risk of
chronic disease and shorter lifespan. These individuals also tend to exhibit accelerated …

Research examining the association between exposure to a wide range of adverse
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …

Adverse childhood experiences have been consistently linked with physical and mental
health disorders in adulthood that may be mediated, in part, via the effects of such …

Emerging research suggests associations of physical and psychosocial stressors with
epigenetic aging. Although this work has included early-life exposures, data on maternal …

Adverse childhood experiences (ACE) are associated with HPA axis dysregulation at
younger ages, but there is scarcity of evidence for this association at older ages. To add to …

Introduction: Frailty in older adults, characterized by a decline in multiple physiological
systems and increasing vulnerability to loss of independence, disability, and death, is a …

Experiencing adversity in childhood and adolescence, including stressful life events (SLEs),
may accelerate the pace of development, leading to adverse mental and physical health …

In this article, we suggest that aging and development are two sides of the same coin, and
that developing a comprehensive understanding of health and disease risk requires …

Abstract Background and Objectives Adverse childhood events (ACEs) have been
associated with increased health risks later in life. However, it is unclear whether ACEs may …

Background: Population-level prevalence estimates for a broad range of adverse childhood
experiences (ACEs), which are known to affect health across the lifespan, are currently …