With a falling birth rate and increasing life expectancy we are experiencing dramatic
demographic changes that result in an ever ageing population. Aging is accompanied by …

The age-related dysregulation and decline of the immune system—collectively termed
“immunosenescence”—has been generally associated with an increased susceptibility to …

Successful vaccination of the elderly against important infectious pathogens that cause high
morbidity and mortality represents a growing public health priority. Building on the theme of …

Aging is associated with declines in immune system function, or 'immunosenescence',
leading to progressive deterioration in both innate and adaptive immunity. These changes …

The immune system of the elderly is particularly susceptible to infectious diseases and
displays reduced response to vaccination. The current vaccines, designed for young and …

Older adults are more susceptible to viral and bacterial infection, and experience higher
incidence and severity of infectious diseases. Although vaccination is the most logical …

The increased susceptibility of the elderly to infection presents a major challenge to public
health services. An aging immune system is well documented as the cause of increased …

The unprecedented increase of life expectancy challenges society to protect the elderly from
morbidity and mortality making vaccination a crucial mean to safeguard this population …

With increasing age, the human immune system undergoes characteristic changes, termed
immunosenescence, which lead to increased incidence and severity of infectious diseases …

Average life expectancy is continuously rising in all developed countries, leading to an ever-
increasing elderly population. Of the many functions of the body affected by the complex …