[HTML][HTML] Epigenetic clock analysis of diet, exercise, education, and lifestyle factors
Behavioral and lifestyle factors have been shown to relate to a number of health-related
outcomes, yet there is a need for studies that examine their relationship to molecular aging …
outcomes, yet there is a need for studies that examine their relationship to molecular aging …
[HTML][HTML] Stress, diet, exercise: Common environmental factors and their impact on epigenetic age
F Galkin, O Kovalchuk, D Koldasbayeva… - Ageing Research …, 2023 - Elsevier
Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …
health conditions in clinical and research settings. They have enabled geroscientists to …
[HTML][HTML] The epigenetic landscape of age-related diseases: the geroscience perspective
In this review, we summarize current knowledge regarding the epigenetics of age-related
diseases, focusing on those studies that have described DNA methylation landscape in …
diseases, focusing on those studies that have described DNA methylation landscape in …
Genetic evidence for causal effects of socioeconomic, lifestyle, and cardiometabolic factors on epigenetic-age acceleration
Abstract GrimAge acceleration (GrimAgeAccel) and PhenoAge acceleration
(PhenoAgeAccel) are DNA methylation-based markers of accelerated biological aging …
(PhenoAgeAccel) are DNA methylation-based markers of accelerated biological aging …
The socioeconomic gradient in epigenetic ageing clocks: evidence from the multi-ethnic study of atherosclerosis and the health and retirement study
Epigenetic clocks have been widely used to predict disease risk in multiple tissues or cells.
Their success as a measure of biological ageing has prompted research on the connection …
Their success as a measure of biological ageing has prompted research on the connection …
Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges
Human lifespan variation is mainly determined by environmental factors, whereas the
genetic contribution is 25–30% and expected to be polygenic. Two complementary fields go …
genetic contribution is 25–30% and expected to be polygenic. Two complementary fields go …
Epigenetic age is associated with baseline and 3-year change in frailty in the Canadian Longitudinal Study on Aging
Background The trajectory of frailty in older adults is important to public health; therefore,
markers that may help predict this and other important outcomes could be beneficial …
markers that may help predict this and other important outcomes could be beneficial …
Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN study
Background Recently, epigenetic age acceleration—or older epigenetic age in comparison
to chronological age—has been robustly associated with mortality and various morbidities …
to chronological age—has been robustly associated with mortality and various morbidities …
Tracking the epigenetic clock across the human life course: a meta-analysis of longitudinal cohort data
Background Epigenetic clocks based on DNA methylation yield high correlations with
chronological age in cross-sectional data. Due to a paucity of longitudinal data, it is not …
chronological age in cross-sectional data. Due to a paucity of longitudinal data, it is not …
Associations of age, sex, race/ethnicity, and education with 13 epigenetic clocks in a nationally representative US sample: the Health and Retirement Study
Background Many DNA methylation-based indicators have been developed as summary
measures of epigenetic aging. We examine the associations between 13 epigenetic clocks …
measures of epigenetic aging. We examine the associations between 13 epigenetic clocks …