Exposure to adversity in childhood is associated with elevations in numerous physical and
mental health outcomes across the life course. The biological embedding of early …

Importance Many studies have demonstrated an association between early-life adversity
(ELA) and executive functioning in children and adolescents. However, the aggregate …

Early life adversity (ELA) is associated with poorer health in adulthood, an association
explained, at least in part, by increased engagement in health‐risk behaviors (HRBs). In this …

Substantial evidence has accumulated supporting a causal link between childhood
adversity and risk for poor health years and even decades later. One interpretation of this …

Background Childhood adversity has been previously associated with alterations in brain
structure, but heterogeneous designs, methods, and measures have contributed to mixed …

Background Early life stress (ELS) can compromise development, with higher amounts of
adversity linked to behavioral problems. To understand this linkage, a growing body of …

Adverse childhood experiences (ACEs) increase risk for depression at subsequent ages
and have been linked to accelerated biological aging. We hypothesize that accelerated …

Importance Accelerated aging makes adults more vulnerable to chronic diseases and death.
Whether childhood adversity is associated with accelerated aging processes, and to what …

Objectives. This article examines how processes of cumulative adversity shape heart attack
risk trajectories across the life course. Methods. Our sample includes 9760 Health and …

Childhood adversity is associated with a host of mental and physical health problems across
the lifespan. Individuals who have experienced childhood adversity (eg, child abuse and …