Early life adversity decreases pre-adolescent fear expression by accelerating amygdala PV cell development
Early life adversity (ELA) is associated with increased risk for stress-related disorders later in
life. The link between ELA and risk for psychopathology is well established but the …
life. The link between ELA and risk for psychopathology is well established but the …
Early childhood adversity and late-life depressive symptoms: unpacking mediation and interaction by adult socioeconomic status
Abstract Purpose Adverse childhood experiences (ACEs) have been linked to diminished
health achievement across the life course. However, few studies have rigorously …
health achievement across the life course. However, few studies have rigorously …
[HTML][HTML] Timing of early-life stress and the development of brain-related capacities
EP Hambrick, TW Brawner, BD Perry - Frontiers in behavioral …, 2019 - frontiersin.org
Early-life stress (ELS) poses risks for developmental and mental health problems throughout
the lifespan. More research is needed regarding how specific ELS experiences influence …
the lifespan. More research is needed regarding how specific ELS experiences influence …
The lasting legacy of childhood adversity for disease risk in later life.
Objective: There has been an increased interest in the role of the childhood social
environment in the etiology of adult diseases in recent years. The present study examines …
environment in the etiology of adult diseases in recent years. The present study examines …
Impact of early vs. late childhood early life stress on brain morphometrics
Previous studies of early life trauma suggest that in addition to its emotional impact,
exposure to early life stress (ELS) is associated with alterations in brain structure. However …
exposure to early life stress (ELS) is associated with alterations in brain structure. However …
[HTML][HTML] Social hallmarks of aging: Suggestions for geroscience research
EM Crimmins - Ageing research reviews, 2020 - Elsevier
This paper focuses on the social hallmarks of aging including low lifetime socioeconomic
status, adversity in childhood and adulthood, being a member of a minority group, adverse …
status, adversity in childhood and adulthood, being a member of a minority group, adverse …
Association of timing of adverse childhood experiences and caregiver support with regionally specific brain development in adolescents
Importance Few data are available to inform the associations and timing of the associations
between adversity, caregiver support, and brain outcomes. Consideration of timing has …
between adversity, caregiver support, and brain outcomes. Consideration of timing has …
Mechanisms linking early life stress to adult health outcomes
SE Taylor - Proceedings of the National Academy of …, 2010 - National Acad Sciences
Research relating stress to health has progressed from anecdotal evidence in the 1930s
and 1940s to complex multivariate models that identify underlying longitudinal mechanisms …
and 1940s to complex multivariate models that identify underlying longitudinal mechanisms …
[HTML][HTML] Early life adversity: lasting consequences for emotional learning
HJ Krugers, JM Arp, H Xiong, S Kanatsou… - Neurobiology of …, 2017 - Elsevier
The early postnatal period is a highly sensitive time period for the developing brain, both in
humans and rodents. During this time window, exposure to adverse experiences can …
humans and rodents. During this time window, exposure to adverse experiences can …
Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies
Psychosocial adversity in childhood (eg abuse) and low socioeconomic position (SEP) can
have significant lasting effects on social and health outcomes. DNA methylation-based …
have significant lasting effects on social and health outcomes. DNA methylation-based …