Epigenetics and oxidative stress in aging
A Guillaumet-Adkins, Y Yañez… - Oxidative medicine …, 2017 - Wiley Online Library
Aging is a multifactorial process characterized by the progressive loss of physiological
functions, leading to an increased vulnerability to age‐associated diseases and finally to …
functions, leading to an increased vulnerability to age‐associated diseases and finally to …
[HTML][HTML] Higher diet quality relates to decelerated epigenetic aging
Background DNA methylation–based epigenetic age measures have been used as
biological aging markers and are associated with a healthy lifespan. Few population-based …
biological aging markers and are associated with a healthy lifespan. Few population-based …
Physical activity is associated with slower epigenetic ageing—Findings from the Rhineland study
Epigenetic ageing, ie, age‐associated changes in DNA methylation patterns, is a sensitive
marker of biological ageing, a major determinant of morbidity and functional decline. We …
marker of biological ageing, a major determinant of morbidity and functional decline. We …
Genetic evidence for causal effects of socioeconomic, lifestyle, and cardiometabolic factors on epigenetic-age acceleration
Abstract GrimAge acceleration (GrimAgeAccel) and PhenoAge acceleration
(PhenoAgeAccel) are DNA methylation-based markers of accelerated biological aging …
(PhenoAgeAccel) are DNA methylation-based markers of accelerated biological aging …
An older subjective age is related to accelerated epigenetic aging.
Y Stephan, AR Sutin, M Luchetti… - Psychology and …, 2021 - psycnet.apa.org
The present study examined the prospective association between subjective age and
epigenetic clock in 2,253 adults (Mean age= 67.40, SD= 8.17) from the Health and …
epigenetic clock in 2,253 adults (Mean age= 67.40, SD= 8.17) from the Health and …
Epigenetics and aging
S Pal, JK Tyler - Science advances, 2016 - science.org
Over the past decade, a growing number of studies have revealed that progressive changes
to epigenetic information accompany aging in both dividing and nondividing cells …
to epigenetic information accompany aging in both dividing and nondividing cells …
Life stress, glucocorticoid signaling, and the aging epigenome: Implications for aging-related diseases
Life stress has been associated with accelerated cellular aging and increased risk for
developing aging-related diseases; however, the underlying molecular mechanisms remain …
developing aging-related diseases; however, the underlying molecular mechanisms remain …
Developmental tuning of epigenetic clock
A Vaiserman - Frontiers in genetics, 2018 - frontiersin.org
Research in the field of gerontology has traditionally focused on later life stages. There is
increasing evidence, however, that both the rate of age-related functional decline and the …
increasing evidence, however, that both the rate of age-related functional decline and the …
Making sense of the ageing methylome
Over time, the human DNA methylation landscape accrues substantial damage, which has
been associated with a broad range of age-related diseases, including cardiovascular …
been associated with a broad range of age-related diseases, including cardiovascular …
DNA methylation aging clocks: challenges and recommendations
Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …