In a study designed to determine whether cytotoxic T lymphocytes contribute to immunity
against influenza virus infection, we inoculated 63 volunteers intranasally with live …

The human cytotoxic T lymphocyte (CTL) response to challenge with influenza A vaccine
was studied. Six of eight volunteers given killed whole influenza virus A/USSR (H1N1) …

Human peripheral blood lymphocytes have been sensitized in vitro to influenza virus
antigen. After an induction period of 4–14 days, cytotoxic cells which lyse autologous …

Specificity of cytotoxic T-cell function was investigated for a range of different influenza
viruses. T cells from mice immunized with A or B strain influenza viruses, or with vaccinia …

This report examines the requirement for infectious virus in the induction of influenza virus-
specific cytotoxic T cells. Infectious influenza virus was found to be highly efficient at …

Abstract Influenza-A-virus-specific, HLA-restricted, cytotoxic T-cell immunity, measured in
189 volunteers in the six years 1977-82, showed a sharp decline from 1978. It is shown that …

We tested two biological properties of a continuously growing mouse cytotoxic T cell line, L4,
which is specific for influenza A virus and has been cloned and recloned many times. We …

Conditions are described for the generation and detection of murine cytotoxic cells which
lyse influenza virus-infected target cells. A number of criteria indicated that most and …

This paper deals with the generation and specificity of cytotoxic T cells directed to cells
infected with type A influenza viruses. Mice were primed in vivo and their spleen cells …

Cytotoxic T cells are present in the lungs and the bronchoalveolar washings of mice infected
intravenously (iv) or intranasally (in) with live influenza A/WSN virus. After iv injection …