… brain and blood compartments. In this review, we discuss mechanisms by which SARS-CoV-2 …
dysfunction associated with coronavirus disease of 2019 (COVID-19), which is caused by …

… and brain damage. Then, we analyzed and described the possible mechanisms causative
of brain injury after SARS-CoV-2 infection. We proposed that potential routes of SARS-CoV-2 …

… SARS-CoV-2 mRNA has been recovered from the cerebrospinal fluid 4 , suggesting it can
… the blood–brain barrier (BBB). Other coronaviruses, including the closely related SARS virus …

… COVID-19 patients with signs of encephalopathy were tested for antibodies to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) in … Blood-brain barrier (BBB) integrity and …

… SARS-CoV-2 invades the brain and infects brain vascular endothelial cells, leading to brain
… Besides, we found the co-localization of SARS-CoV-2-S with blood vessels in the cortex of …

… While BCECs were not compromised in their paracellular tightness, we found SARS-CoV-2 …
of virus across the blood-brain barrier (BBB) in vitro. Moreover, entry of SARS-CoV-2 into …

… To probe the effects of SARS-CoV-2 infection on the human brain in an organ–organ context,
we established an integrated lung–brain MPS that enables recapitulation of the essential …

… However, the current evidence does indicate that the SARS-CoV-2 virus can use … the virus
may also enter the brain through the blood–brain barrier (BBB). We discuss how the virus may …

… (RBD) and the S2 subunit. First, using postmortem brain tissue, we show that the angiotensin
converting enzyme 2 or ACE2 (a known binding target for the SARS-CoV-2 spike protein), …

… However, we believe, that SARS-COV-2 associated endothelial cell dysfunction preludes
the neuropathology associated with SARS-COV-2 that is observed in COVID-19 infected …