… Consequently, the virus’ ability to infect brain cells and induce the inflammatory response … patients with SARS-CoV-2 infection and its association with the blood-brainbarrier integrity. …
S Krasemann, U Haferkamp, S Pfefferle, MS Woo… - Stem cell reports, 2022 - cell.com
… While BCECs were not compromised in their paracellular tightness, we found SARS-CoV-2 … of virus across the blood-brainbarrier (BBB) in vitro. Moreover, entry of SARS-CoV-2 into …
… However, we believe, that SARS-COV-2 associated endothelial cell dysfunction preludes the neuropathology associated with SARS-COV-2 that is observed in COVID-19 infected …
L Zhang, L Zhou, L Bao, J Liu, H Zhu, Q Lv… - Signal transduction and …, 2021 - nature.com
… invading the brains of humans and model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the blood–brainbarrier (BBB). Herein, SARS-CoV-2 RNA was …
… –SARS-CoV-2 IgG intrathecal synthesis, and 3 others had disruption of the blood-brainbarrier. … negative for autoimmune encephalitis antibodies and SARS-CoV-2 by PCR. None of the …
EM Rhea, AF Logsdon, KM Hansen, LM Williams… - Nature …, 2021 - nature.com
… SARS-CoV-2 mRNA has been recovered from the cerebrospinal fluid 4 , suggesting it can … blood–brainbarrier (BBB). Other coronaviruses, including the closely related SARSvirus that …
O Constant, J Barthelemy, K Bollore, E Tuaillon… - Frontiers in …, 2021 - frontiersin.org
… Finally, using serum samples from COVID-19 patients, we highlighted strong concentrations of pro… of brain access following SARS-CoV-2 infection does not seem to be directed by brain …
… 2 (ACE2) with increased activity of the transmembrane protease serine 2 (TMPRSS2) and cathepsin L in SARS-CoV-2 … response and blood brainbarrier disruption. Furthermore, …
P Wang, L Jin, M Zhang, Y Wu, Z Duan, Y Guo… - Nature Biomedical …, 2023 - nature.com
… blood–brainbarrier (BBB) tissue chips that recapitulates neuropathogenesis associated with infection by SARS-CoV-2. Direct exposure of the BBB chip to SARS-CoV-2 caused mild …