[HTML][HTML] Mapping of SARS-CoV-2 brain invasion and histopathology in COVID-19 disease

GE Serrano, JE Walker, R Arce, MJ Glass, D Vargas… - MedRxiv, 2021 - ncbi.nlm.nih.gov
… The rate of SCV2 brain invasion in the current study has … the large number of brain regions
assayed, 16 brain regions per … the positive brain samples represent true brain invasion are the …

Does SARSCov2 invade the brain? Translational lessons from animal models

S Natoli, V Oliveira, P Calabresi… - European journal of …, 2020 - Wiley Online Library
coronavirus disease (COVID-19) outbreak, caused by the novel severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2… properties of this virus. Indeed, neurological sequelae of …

SARS-CoV-2: is there neuroinvasion?

C McQuaid, M Brady, R Deane - Fluids and Barriers of the CNS, 2021 - Springer
… , uniqueness of the brain, and the pre-existing medical conditions that affect brain. The main
… of SARS-CoV-2 into brain, at present, compared to its invasion of the inhalation pathways. …

Possible routes of SARSCoV2 invasion in brain: in context of neurological symptoms in COVID19 patients

A Kumar, V Pareek, P Prasoon, MA Faiq… - Journal of …, 2020 - Wiley Online Library
… There is also a possibility that, there may be multiple routes of SARS-CoV-2 entry into the
brain… routes of SARS-CoV-2 brain entry based on the emerging evidence for this virus, and that …

Neuroinvasion of SARSCoV2 may play a role in the breakdown of the respiratory center of the brain

J Dey, MT Alam, S Chandra, J Gupta… - Journal of medical …, 2021 - Wiley Online Library
… receptors on capillary endothelium and encephalopathy observed in the BBB of COVID-19
patients suggests that SARS-CoV-2 might invade the CNS by infiltrating through BBB. …

Neuropathological findings from COVID19 patients with neurological symptoms argue against a direct brain invasion of SARSCoV2: A critical systematic review

G Cosentino, M Todisco, N Hota… - European journal of …, 2021 - Wiley Online Library
SARS-CoV-2–related brain pathology, including assessment of viral proteins and RNA in
brain … the etiology of neurological symptoms in COVID-19 patients. Moreover, incorporation of …

Neurological complications and infection mechanism of SARS-COV-2

D Wan, T Du, W Hong, L Chen, H Que, S Lu… - Signal Transduction and …, 2021 - nature.com
… path for brain invasion by SARS-CoV-2. Recent RNA-Seq studies have found that ACE2 is
elevated in the substantia nigra, ventricles, olfactory bulb, posterior cingulate cortex, posterior …

Evidence of central nervous system infection and neuroinvasive routes, as well as neurological involvement, in the lethality of SARSCoV2 infection

JM Liu, BH Tan, S Wu, Y Gui, JL Suo… - Journal of medical …, 2021 - Wiley Online Library
… In addition, this study shows that SARS-CoV-2 might invade the brain via retrograde
axonal transmission along gustatory, olfactory, and trigeminal pathways at the early stage of …

SARS-CoV-2 invasion of the central nervous: a brief review

R Siddiqui, MR Mungroo, NA Khan - Hospital Practice, 2021 - Taylor & Francis
… CNS involvement in COVID-19, and to identify potential regions of the brain that may be …
syndrome coronavirus 2 (SARS-CoV-2) and its possible route of entry into the brain to identify its …

SARS-CoV-2 productively infects human brain microvascular endothelial cells

RC Yang, K Huang, HP Zhang, L Li, YF Zhang… - Journal of …, 2022 - Springer
… However, we demonstrated that SARS-CoV-2 invasion of the brain increased the BBB
permeability by downregulating and redistributing TJ proteins. Therefore, damaging the BBB …