What can cerebrospinal fluid testing and brain autopsies tell us about viral neuroinvasion of SARSCoV2

YC Li, Y Zhang, BH Tan - Journal of Medical Virology, 2021 - Wiley Online Library
coronavirus 2 (SARS-CoV-2) infection, we analyzed the existing literature on viral neuroinvasion
of SARS-CoV-2 in coronavirus disease 2019 (COVID-19invasion of SARS-CoV-2 in the …

Neuroinvasive potential of SARSCoV2 with neuroradiological and neuropathological findings: is the brain a target or a victim?

RA Franca, L Ugga, E Guadagno, D Russo… - Apmis, 2021 - Wiley Online Library
… It is worth remembering that previously we explained how the blood–brain barrier damage
may be involved in the brain invasion though the hematogenous rout, and therefore, it is …

The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

S Krasemann, U Haferkamp, S Pfefferle, MS Woo… - Stem cell reports, 2022 - cell.com
… serine subtype 2 (TMPRSS2) inhibitor nafamostat. Together, our data provide strong
support for SARS-CoV-2 brain entry across the BBB resulting in increased interferon signaling. …

Interactions of SARS-CoV-2 with the blood–brain barrier

MA Erickson, EM Rhea, RC Knopp… - International Journal of …, 2021 - mdpi.com
… direct and indirect SARS-CoV-2 interactions with the brain. In … in SARS-CoV-2 infections that
could contribute to COVID-19-… ceramide to invade immune cells, but brain endothelial cells, …

SARSCoV2 and the brain: A review of the current knowledge on neuropathology in COVID19

A Maiese, AC Manetti, C Bosetti, F Del Duca… - Brain …, 2021 - Wiley Online Library
… and selected those that analyzed brain histology in COVID-19 patients. Disagreements …
can cause CNS infections and animal models indicated they invade the blood-brain barrier (…

SARS-COV2 alters blood brain barrier integrity contributing to neuro-inflammation

JL Reynolds, SD Mahajan - Journal of Neuroimmune Pharmacology, 2021 - Springer
… neuro-invasion of SARS-COV-2. … , that SARS-COV-2 associated endothelial cell dysfunction
preludes the neuropathology associated with SARS-COV-2 that is observed in COVID-19

[HTML][HTML] SARS-CoV2 entry and spread in the lymphatic drainage system of the brain

M Bostancıklıoğlu - Brain, behavior, and immunity, 2020 - ncbi.nlm.nih.gov
Coronavirus 2 (SAR-CoV2) has been shown to invade brain … certainty about how it can
invade. Researchers suppose that … , and SARS-CoV2, SARS-CoV2 could be a neurotrophic virus

Long-term effects of SARS-CoV-2 infection on human brain and memory

Q Ding, HJ Zhao - Cell Death Discovery, 2023 - nature.com
SARS-CoV-2 invading human brain and the molecular basis of SARS-CoV-2 infection
interfering with human brain … cell death, the persistence of SARS-CoV-2 infection, microclots and …

The olfactory route is a potential way for SARS-CoV-2 to invade the central nervous system of rhesus monkeys

L Jiao, Y Yang, W Yu, Y Zhao, H Long, J Gao… - Signal transduction and …, 2021 - nature.com
… Consistent with the study that examined viral protein in brain sections from SARS-CoV-2-infected
hACE2 knock-in mice, 8 we have detected the viral NP expression in neurons, …

Involvement of the nervous system in SARS-CoV-2 infection

H Li, Q Xue, X Xu - Neurotoxicity research, 2020 - Springer
… be invaded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and that 36.4%
of COVID-19 … a SARS-CoV-2 may enter the brain through the olfactory nerve endings and …