… Whether this results in virus spread into the brain parenchyma in vivo is unknown. … of the
frequency and routes of CNS invasion by SARS-CoV-2, as well as how these potential routes of …

… points for the brain invasion, allowing SARS-CoV-2 to infect the … , SARS-CoV-2 is capable
to disseminate from the brain to … clinically observed phenomena in CoVID-19 patients, such …

… hypothesis that there is direct invasion of the central nervous system (CNS) by SARS-CoV-…
findings and the presence of SARS-CoV-2 virus in postmortem brain samples. For comparison…

… diseases in patients with COVID-19, the gut–brain axis likely plays a vital role in SARS-…
Therefore, we propose that SARS-CoV-2 can retrogradely invade the glial cells of the …

… brain barrier to the brain. Also, more recent research has revealed that SARS-CoV-2 can
invade the peripheral lymphatic vessels connecting with the glymphatic system of the brain. …

… SARS-CoV-2 neuro-invasion studies in vivo are still rare, despite the fact that other beta-coronaviruses
have shown similar properties. Neural (olfactory or vagal) and hematogenous (…

… invade the central nervous system inducing neurological diseases. The infection of SARS-CoV
has been reported in the brains … whether the potential invasion of SARS-CoV2 is partially …

… for the transsynaptic spread of the virus in the CNS, the effect … brain barrier (BBB) and the
persistence of SARS-CoV-2 in the … After brain invasion, primary effect of SARS-CoV-2 emerges …

… to infect immune cells in the periphery that subsequently invade the CNS also warrants
consideration. Infected macrophages have been reported (Yao et al., 2020), strengthening the …

… SARS-CoV-2 infection on the human brain in an organ–organ context, we established an
integrated lung–brain … We found that SARS-CoV-2 showed a fragile ability to invade the brain …