[HTML][HTML] Neurological involvement in SARS-CoV-2 infection: a clinical systematic review

P Scoppettuolo, S Borrelli, G Naeije - Brain, behavior, & immunity-health, 2020 - Elsevier
… Apart from a direct virus invasion, SARS-CoV-2 neurological damages can be related to
the systemic inflammatory response, due to the innate immunity activation that leads in severe …

The hypothalamus as a hub for putative SARS-CoV-2 brain infection

S Nampoothiri, F Sauve, G Ternier, D Fernandois… - BioRxiv, 2020 - biorxiv.org
… A post-mortem patient brain shows viral invasion and replication in both the olfactory
bulb and the hypothalamus, while animal studies indicate that sex hormones and metabolic …

Neuromechanisms of SARS-CoV-2: a review

MF DosSantos, S Devalle, V Aran, D Capra… - Frontiers in …, 2020 - frontiersin.org
… literature that indicates that SARS-CoV-2 can invade the nervous system. We … SARS-CoV-2
enters through the olfactory nerve and reaches the brain, in the same manner as SARS-CoV

The emergence of a novel coronavirus (SARSCoV2) disease and their neuroinvasive propensity may affect in COVID19 patients

HC Yashavantha Rao… - Journal of medical …, 2020 - Wiley Online Library
… similarities between SARS-CoV and SARS-CoV-2 in various … potent invasion of SARS-CoV-2
may affect in COVID-19 patients… for brain illness caused by COVID-19 would include type 2

[HTML][HTML] What SARS-CoV-2 does to our brains

T Aschman, R Mothes, FL Heppner, H Radbruch - Immunity, 2022 - cell.com
… observed after SARS-CoV-2 infection could be (1) directly caused by the virus infecting brain
cells, (2) indirectly by our body’s local or systemic immune response toward the virus, (3) by …

COVID-19-associated neurological disorders: the potential route of CNS invasion and blood-brain barrier relevance

A Achar, C Ghosh - Cells, 2020 - mdpi.com
SARS-CoV-2. This review highlights the possible routes by which SARS-CoV-2 may invade
the central nervous system (CNS) and provides insight into recent case reports of COVID-19

Infection mechanism of SARS-COV-2 and its implication on the nervous system

EE Reza-Zaldívar, MA Hernández-Sapiéns… - Frontiers in …, 2021 - frontiersin.org
… During HEV67 infection, the first coronavirus reported invading porcine brains; the nasal
mucosa, lung, and small intestine are first infected. Then is spread to medullary neurons via …

SARS-CoV-2 detected in olfactory neurons

S Lemprière - Nature Reviews Neurology, 2021 - nature.com
… between SARS-CoV-2 and the brain, but whether viral invasion of the … observed in patients
with COVID-19 is not entirely clear. … of the interactions between SARS-CoV-2 and the brain

COVID-19 and SARS-Cov-2 infection: pathophysiology and clinical effects on the nervous system

H Abboud, FZ Abboud, H Kharbouch, Y Arkha… - World neurosurgery, 2020 - Elsevier
… The usual lack of permeability of cerebral blood vessels represents a barrier to virus invasion,
but also a barrier to viruses' elimination in case of brain invasion. Given the lack of major …

SARS-CoV-2, ACE2 expression, and systemic organ invasion

UM Ashraf, AA Abokor, JM Edwards… - Physiological …, 2021 - journals.physiology.org
… of the biology of SARS-CoV-2 infection, the varied clinical outcomes of COVID-19, and its
potential … Neurons within the brain have been shown to be targeted by SARS-CoV (76). In vivo …