[HTML][HTML] Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics

C Muus, MD Luecken, G Eraslan, L Sikkema… - Nature medicine, 2021 - nature.com
… We identify cross-tissue and tissue-specific gene programs enriched in immune-associated
genes in ACE2 + TMPRSS2 + cells and highlight other proteases that are significantly …

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

DH Brann, T Tsukahara, C Weinreb, M Lipovsek… - Science …, 2020 - science.org
… Expression of CoV-2 entry genes in different cell types of mouse olfactory epithelium To
further explore the distribution of CoV-2 cell entry genes in the olfactory system we turned to the …

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity

Z Inde, BA Croker, C Yapp, GN Joshi, J Spetz… - Science …, 2021 - science.org
… Here, we investigate how expression of viral entry and cell death genes in the lung might
vary among different age groups and how this variation relates to known differences in disease …

[HTML][HTML] SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

W Sungnak, N Huang, C Bécavin, M Berg, R Queen… - Nature medicine, 2020 - nature.com
SARS-CoV-2 potential tropism by surveying expression of viral entry-associated genes in
single-cell … intestinal epithelial cells, potentially explaining the high efficiency of SARS-CoV-…

[HTML][HTML] SARS-CoV-2 receptors and entry genes are expressed in the human olfactory neuroepithelium and brain

L Fodoulian, J Tuberosa, D Rossier, M Boillat, C Kan… - Iscience, 2020 - cell.com
… Sustentacular cells thus represent a potential entry door for SARS-CoV-2 in a neuronal sensory
… OR genes, olfactory transduction cascade specific genes, and SARS-CoV-2 entry genes

[HTML][HTML] Expression Pattern of the SARS-CoV-2 Entry Genes ACE2 and TMPRSS2 in the Respiratory Tract

Y Liu, HQ Qu, J Qu, L Tian, H Hakonarson - Viruses, 2020 - mdpi.com
… as well as the aerosol transmission of the virus. With ACE2 and TMPRSS2 as the major
entry genes, however, other potential entry genes of SARS-CoV-2, namely FURIN, DPP4, and …

[HTML][HTML] Genetic variability in the expression of the SARS-CoV-2 host cell entry factors across populations

L Ortiz-Fernández, AH Sawalha - Genes & Immunity, 2020 - nature.com
… We calculated a cumulative genetic expression score (GES) for ACE2 and TMPRSS2, as
a measure to estimate host genetic determinants of viral entry of SARS-CoV-2. We evaluated …

[PDF][PDF] Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients

D Brann, T Tsukahara, C Weinreb, DW Logan… - BioRxiv, 2020 - biorxiv.org
… and single cell RNA-Seq datasets to identify cell types in the … by SARSCoV-2 (CoV-2), the
causal agent in COVID-19. We find … not express two key genes required for CoV-2 entry, ACE2 …

Gene of the month: the 2019-nCoV/SARS-CoV-2 novel coronavirus spike protein

TS Pillay - Journal of clinical pathology, 2020 - jcp.bmj.com
… to SARS-CoV can confer some very limited immunity to SARS-CoV-2 based on the observation
that SARS-CoV antibodies are able to prevent the entry of SARS-CoV-2 into cells15 16 …

[HTML][HTML] SARS-CoV-2 entry genes are most highly expressed in nasal goblet and ciliated cells within human airways

W Sungnak, N Huang, C Bécavin, M Berg… - ArXiv, 2020 - ncbi.nlm.nih.gov
… on alveolar epithelial cells as the primary point of entry and viral replication 8,21,22 . …
genes associated with SARS-CoV-2 pathogens at cellular resolution, we interrogated single-cell