Comparative transcriptome analysis of SARS-CoV, MERS-CoV, and SARS-CoV-2 to identify potential pathways for drug repurposing
… available SARS-CoV and MERS-CoV in-vitro transcriptome … point after both SARS-CoV
and MERS-CoV infection. We … of SARS-CoV and MERS-CoV with that of SARS-CoV-2 at the …
and MERS-CoV infection. We … of SARS-CoV and MERS-CoV with that of SARS-CoV-2 at the …
[HTML][HTML] In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age
… transcriptome (>500,000, median 1.61 × 10 6 ) to examine gene expression changes as
a result of reverse transcription polymerase chain reaction (RT-PCR)-confirmed SARS-CoV-2 …
a result of reverse transcription polymerase chain reaction (RT-PCR)-confirmed SARS-CoV-2 …
Specific immune-regulatory transcriptional signatures reveal sex and age differences in SARS-CoV-2 infected patients
… Here, we characterize a previously unnoticed interconnected transcriptome network … NMI)
genes accordingly to sex and age. We found specific transcriptome signatures in RNASeq from …
genes accordingly to sex and age. We found specific transcriptome signatures in RNASeq from …
Cumulative effect of aging and SARS-CoV2 infection on poor prognosis in the elderly: Insights from transcriptomic analysis of lung and blood
U Bhattacharyya, BK Thelma - bioRxiv, 2020 - biorxiv.org
… iii) a similar overlap between host genes interacting with SARS-CoV-2 and aging blood
transcriptome. … genes in the healthy aging group that overlap SARS CoV-2 associated and SARS-…
transcriptome. … genes in the healthy aging group that overlap SARS CoV-2 associated and SARS-…
[HTML][HTML] Age-dependent pathogenic characteristics of SARS-CoV-2 infection in ferrets
… Recently, a transcriptome analysis study of COVID-19 patients demonstrated robust induction
of … In this study, transcriptome analysis during the early stage of SARS-CoV-2 infection in …
of … In this study, transcriptome analysis during the early stage of SARS-CoV-2 infection in …
[HTML][HTML] Impact of BNT162b first vaccination on the immune transcriptome of elderly patients infected with the B. 1.351 SARS-CoV-2 variant
L Knabl, HK Lee, M Wieser, A Mur, A Zabemigg… - Research …, 2021 - ncbi.nlm.nih.gov
… immune transcriptome of six elderly individuals (average age 82 … Immune transcriptomes
were established from PBMCs … immunity and COVID-19-SARS-CoV-2 infection were highly …
were established from PBMCs … immunity and COVID-19-SARS-CoV-2 infection were highly …
[HTML][HTML] Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection
M Salgado-Albarrán, EI Navarro-Delgado… - NPJ systems biology …, 2021 - nature.com
… are not fully described for SARS-CoV-2. In this study, we analyzed multiple transcriptomes
obtained from cell lines infected with MERS-CoV, SARS-CoV, and SARS-CoV-2, and from …
obtained from cell lines infected with MERS-CoV, SARS-CoV, and SARS-CoV-2, and from …
[HTML][HTML] Characterization of the SARS-CoV-2 host response in primary human airway epithelial cells from aged individuals
B Subramaniyan, JL Larabee, M Bodas, AR Moore… - Viruses, 2021 - mdpi.com
… -2 infected cells (n = 4 donors) were harvested as a function of time post-infection (24–96
h) and the genome-wide transcriptome changes in response to the SARS-CoV-2 infection …
h) and the genome-wide transcriptome changes in response to the SARS-CoV-2 infection …
[HTML][HTML] Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection
PP Sfikakis, KM Verrou… - Frontiers in …, 2021 - frontiersin.org
… SARS-CoV-2 antibodies was 1.58%, whereas 49% of the seropositive individuals denied
having had any clinical symptom compatible with previous SARS-CoV-… associated with age or …
having had any clinical symptom compatible with previous SARS-CoV-… associated with age or …