SARSCoV‐2: A comprehensive review from pathogenicity of the virus to clinical consequences

M Lotfi, N Rezaei - Journal of medical virology, 2020 - Wiley Online Library
… In conclusion, SARS-CoV-2 is a mysterious virus, and the contemporary pieces of knowledge
are vague and inadequate. Although scientists are making an effort to develop proper …

[HTML][HTML] The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

L Bao, W Deng, B Huang, H Gao, J Liu, L Ren, Q Wei… - Nature, 2020 - nature.com
… receptor for severe acute respiratory syndrome coronavirus (SARS-CoV) 2 . Here we …
SARS-CoV-2 and studied the pathogenicity of the virus. We observed weight loss as well as virus

Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron

H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin… - Nature, 2022 - nature.com
… To examine whether the Omicron variant is also attenuated in vivo, we first compared
virus propagation of Omicron with SARS-CoV-2 WT and the Delta variant in the K18-hACE2 …

Mutations in SARS-CoV-2; Consequences in structure, function, and pathogenicity of the virus

B Bakhshandeh, Z Jahanafrooz, A Abbasi, MB Goli… - Microbial …, 2021 - Elsevier
… Overall, the detection of all mutations in SARS-CoV-2 and their relations with pathological
… of the SARS-CoV-2 and related variations in virus structure and pathogenicity in different …

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

A Saito, T Irie, R Suzuki, T Maemura, H Nasser, K Uriu… - Nature, 2022 - nature.com
… effect of the P681R mutation on viral replication and the pathogenicity of SARS-CoV-2, we
intranasally infected Syrian hamsters with the D614G and D614G/P681R viruses. The D614G-…

Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

AB Gussow, N Auslander, G Faure… - Proceedings of the …, 2020 - National Acad Sciences
… Here we analyze the genome of the virus that causes COVID-19, SARS-CoV-2, along …
SARS-CoV-2 and the viruses behind the two previous deadly coronavirus outbreaks, SARS-CoV

Patient-derived mutations impact pathogenicity of SARS-CoV-2

H Yao, X Lu, Q Chen, K Xu, Y Chen, L Cheng, F Liu… - MedRxiv, 2020 - medrxiv.org
… on the pathogenicity of SARS-CoV-2. This is crucial in our understanding of the viral infectious
… To address this, we characterized 11 SARS-CoV-2 viral isolates from patients admitted to …

Comparative review of SARS-CoV-2, SARS-CoV, MERS-CoV, and influenza a respiratory viruses

Z Abdelrahman, M Li, X Wang - Frontiers in immunology, 2020 - frontiersin.org
… a comparative study of four pathogenic viruses that primarily attack the … , SARS-CoV-2,
severe acute respiratory syndrome (SARS-CoV), Middle East respiratory syndrome (MERS-CoV), …

Basic virology of SARS-CoV 2

V Ravi, S Saxena, PS Panda - Indian journal of medical microbiology, 2022 - Elsevier
… less pathogenic compared to SARS-CoV and MERS-CoV, considered to be highly pathogenic
… Many aspects of virus biology, SARS-CoV-2, a novel virus have been unravelled within a …

From SARS to SARS-CoV-2, insights on structure, pathogenicity and immunity aspects of pandemic human coronaviruses

N Kirtipal, S Bharadwaj, SG Kang - Infection, Genetics and Evolution, 2020 - Elsevier
… current understanding on the viral genome integrity of known pandemic virus against
SARS-CoV-2. We also consider the host immune response and viral evasion based on available …