[HTML][HTML] Identification of COVID-19-associated DNA methylation variations by integrating methylation array and scRNA-Seq data at cell-type resolution

G Wang, Z Xiong, F Yang, X Zheng, W Zong, R Li… - Genes, 2022 - mdpi.com
… in the accumulation of massive data and corresponding phenotype … DNA methylation array
data at the bulk level, scRNA-seq data, and the regulatory relationship between methylation

DNA methylation disruption reshapes the hematopoietic differentiation landscape

F Izzo, SC Lee, A Poran, R Chaligne, F Gaiti, B Gross… - Nature …, 2020 - nature.com
… We hypothesized that differences in CpG density of DNA-… methylation level changes (Fig.
4a), supported by the association between transcription factor motif sensitivity to methylation

Integrative analyses of scRNA-seq, bulk mRNA-seq, and DNA methylation profiling in depressed suicide brain tissues

Y Zhou, L Xiong, J Chen✉… - International journal of …, 2023 - academic.oup.com
… multi-omics data from bulk mRNA-seq, snRNA-seq, and DNA methylation data to discover
… were finally found to share changes across transcription, DNA methylation, and 2 different …

Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single‐cell analysis

J Castillo‐Fernandez, E Herrera‐Puerta… - Aging …, 2020 - Wiley Online Library
changes in DNA methylationchanges to methylation changes in the same oocyte, indicating
that loss of gene expression fidelity in the aged oocyte can result in altered DNA methylation

[HTML][HTML] DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

C Angermueller, HJ Lee, W Reik, O Stegle - Genome biology, 2017 - Springer
… effects from variations that reflect DNA sequence changes. Although … methylation
variability that is independent of DNA sequencedata obtained from parallel methylation–transcriptome …

[HTML][HTML] … -genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes

S Di Persio, E Leitão, M Wöste, T Tekath, JF Cremers… - Clinical …, 2021 - Springer
… is associated with DNA methylation changes in testicular germ cells at functionally relevant
regions of the genome. We hypothesize that the described DNA methylation changes may …

[HTML][HTML] Simultaneous profiling of transcriptome and DNA methylome from a single cell

Y Hu, K Huang, Q An, G Du, G Hu, J Xue, X Zhu… - Genome biology, 2016 - Springer
… To further understand the correlation of DNA methylation and … cell methylome and transcriptome
sequencing (scMT-seq) method, … variation between cells, we also found differential DNA

[HTML][HTML] Single-cell DNA methylation analysis in cancer

H O'Neill, H Lee, I Gupta, EJ Rodger, A Chatterjee - Cancers, 2022 - mdpi.com
… , DNA methylation (DNAme), can lead to oncogenic phenotypes when abnormal changes
… the other omics methods, such as scRNA sequencing. This can make the process far more …

scMethBank: a database for single-cell whole genome DNA methylation maps

W Zong, H Kang, Z Xiong, Y Ma, T Jin… - Nucleic Acids …, 2022 - academic.oup.com
… scMethBank provides easy access to the gene of interest by gene symbol, gene ID or
genomic location, that will be of benefit to users to explore the methylation status and variation of …

[HTML][HTML] scTEM-seq: single-cell analysis of transposable element methylation to link global epigenetic heterogeneity with transcriptional programs

KV Hunt, SM Burnard, EA Roper, DR Bond, MD Dun… - Scientific Reports, 2022 - nature.com
DNA methylation levels in single-cell data, we first interrogated genome-wide scBS-seq data
… We then correlated DNA methylation levels to changes in gene expression. In our KG1a …