[HTML][HTML] The role of natural products as sources of therapeutic agents for innovative drug discovery

K Dzobo - Comprehensive pharmacology, 2022 - ncbi.nlm.nih.gov
… The use of bioinformatics and computation means that drug discovery can be … discovery.
This review describes the biosynthesis and screening of natural products during drug discovery

Coronaviruses—drug discovery and therapeutic options

A Zumla, JFW Chan, EI Azhar, DSC Hui… - … reviews Drug discovery, 2016 - nature.com
… Substantial efforts are underway to discover new therapeutic agents for CoV infections
and these investigations are based on our understanding of the basic virology of CoVs. …

An overview of drug discovery and development

N Berdigaliyev, M Aljofan - Future medicinal chemistry, 2020 - Taylor & Francis
… The availability to develop therapeutic agents targeted at a particular protein or … drug
discovery. In addition, the establishment of high throughput at different stages of drug discovery and …

Computer-aided drug design applied to marine drug discovery: Meridianins as Alzheimer's disease therapeutic agents

L Llorach-Pares, A Nonell-Canals… - Marine drugs, 2017 - mdpi.com
… This work is aimed to highlight the role of CADD techniques in marine drug discovery and to
… against several protein kinases that could help in the future development of anti-AD drugs. …

[图书][B] Drug discovery: a history

W Sneader - 2005 - books.google.com
… It is helpful to describe the first pure compound to have been discovered in any series of
chemically or developmentally related therapeutic agents as a drug prototype. In certain cases, …

Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents

A Najmi, SA Javed, M Al Bratty, HA Alhazmi - Molecules, 2022 - mdpi.com
… in drug discovery research. Several drugs currently used as therapeutic agents have been
… demonstrated insignificant attention towards natural product drug discovery, mainly due to its …

Fragment-and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response

DM Wilson III, AM Deacon, MAJ Duncton… - Progress in biophysics …, 2021 - Elsevier
… identify rational drug targets, our ability to develop clinical-grade therapeutic agents against
… edge of advancing early drug discovery efforts on novel therapeutic targets. Although we …

The targets of currently used antibacterial agents: lessons for drug discovery

RP Lange, HH Locher, PC Wyss… - Current pharmaceutical …, 2007 - ingentaconnect.com
… and has been recommended for the revitalization of antibiotic discovery [115, 116, 170]. All
drug discovery such as non-antibiotic strategies, narrow-spectrum drugs, phage therapies, …

Drug discovery from natural products

VP Gullo, J McAlpine, KS Lam, D Baker… - Journal of Industrial …, 2006 - academic.oup.com
… Natural product compounds are the source of numerous therapeutic agents. Recent progress
to discover drugs from natural product sources has resulted in compounds that are being …

[图书][B] Drug discovery: a casebook and analysis

RA Maxwell, SB Eckhardt - 2012 - books.google.com
… disease but never get around to doing much about therapy. … how innovative therapeutic
agents were discovered. There … information about the drug discovery process and then see what …