… Background: Increasing the threshold to define a positive D‐dimer could reduce … pulmonary
angiography (CTPA) for a suspected pulmonary embolism (PE) but might increase rates of a …

… pulmonary angiography (CTPA) is frequently requested using diagnostic algorithms for
suspected pulmonary embolism … that doubling the D‐dimer threshold in patients with low pretest …

Importance Pulmonary embolism (PE) is characterized by occlusion of blood flow in a pulmonary
artery, typically due to a thrombus that travels from a vein in a lower limb. The incidence …

… tests for PE diagnosis and highlight some of the additional challenges that might require
adjustments to current diagnostic strategies, such as the reduced clinical suspicion threshold, …

… COVID-19 raises D-dimer (DD) levels even in the absence of pulmonary embolism (PE),
resulting in an increase in computed tomography pulmonary angiogram (CTPA) requests. Our …

… The CPTP-dependent D-dimer threshold has not been … -dimer thresholds as used in the
PEGeD (The Pulmonary Embolism Graduated D-dimer) study (Wells rule with D-dimer threshold …

… Our data favour the use of a D-dimer threshold of 500 ng/mL, considering that higher thresholds
increase specificity … Pulmonary embolism diagnosis was based on filling defects of the …

… workup of suspected Pulmonary Embolism (PE), but its specificity decreases with age. We
evaluated whether using a higher cutoff value for D-dimer could increase the test specificity …

… We hypothesized that an approach using a variable positive/negative threshold would
increase the specificity of quantitative D-dimer testing while maintaining the high NPV of the test. …

… D-dimer threshold in the workup of patients with suspected pulmonary embolism (PE). …
conventional D-dimer threshold with an age-adjusted D-dimer threshold and report the proportion …