… In particular, TLRs 3, 7, and 8 are all localized on the endosomal membrane, and could …
SARS-CoV-2 infection of Calu-3/MRC-5 multicellular spheroids induces the activation of TLR3 …

… subversion effects caused by SARS-CoV-2 [37] and the role of Poly(I:C) as an immune
modulator, we aimed to characterize the inflammatory response induced by SARS-CoV-2 and the …

… TLR mediated NF-κB, MAPK pathway. Hence blocking these specific TLRs may alleviate the
chance of SARS-COV… lacking a TLR3 gene does not render the mice to SARS-COV infection…

… the initiation of innate responses against SARS-CoV-2 infection and the … TLRs in immune
responses against SARS-CoV-2 infection and demonstrate the potential effectiveness of TLR…

… Extracellular domains of TLRs can be homodimers, in the cases of TLRs 3, 4, 5… TLR3
rare variants, as well as the L412F polymorphism in TLR3 that negatively regulates anti-SARS-CoV-…

… mouse β-coronavirus, mouse … SARS-CoV-2 induces senescence in human non-senescent
cells and exacerbates the SASP in human senescent cells through Toll-like receptor-3 (TLR-3…

… expression of Toll-like receptor 3 (TLR3) in SARS-CoV-2 infected cells and can reduce TLR3-…
SARS-CoV-2-infected cells treated with famotidine demonstrate reduced expression levels …

We recently reported that inborn errors of the TLR3-and IRF7-dependent production and
amplification of type I interferons (IFNs) confer a predisposition to life-threatening COVID-19 …

… expression of MyD88 and TLR3, the ranking of … SARS-CoV infection, we hypothesized
that TLR3 signaling may also be involved in the protective innate immune response to SARS-CoV …

… Toll-like receptors recognize the viral RNA – double-stranded RNA (dsRNA) by TLR3 …
TLR3/7/8 to investigate the difference in the genetic predisposition to the susceptibly of SARS-CoV-…