… Toll-like receptors recognize the viral RNA – double-stranded RNA (dsRNA) by TLR3 …
TLR3/7/8 to investigate the difference in the genetic predisposition to the susceptibly of SARS-CoV-…

… the endoplasmic reticulum, such as TLRs 3, 7, 8, and 9 [24,25]. … TLRs in shaping the innate
response in SARS-CoV-2 infection. From the currently available data, it is assumed that TLRs…

… Cytosolic retinoic acid-inducible gene (RIG)-I-like receptors, including RIG-I and MDA-5,
and endosomal Toll-like receptor 3 (TLR3) recognize dsRNAs from intermediates generated …

… Experiments using mouse-adapted SARS-CoV have shown that mice lacking TLR3 or the
signaling adapter TRIF are more susceptible to virus-induced lung pathology and maintain …

… other TLRs are activated by spike protein, we treated macrophages from TLR2- or TLR3-deficient
mice with SARS-CoV and SARS-CoV-2 spike protein. Deficiency of TLR2 or TLR3 did …

… suitable [3] to test the relationship between TLR3 variant and … analysis was not conducted
in SARS-CoV-2 infected cases. … association between SARS-CoV-2 and the TLR-3 rs3775291 …

… , homeostatic chemokines, as well as Toll-like receptor (TLR)-3/4 in COVID-19 have not been
investigated. We aimed to assess the expression levels and roles of TLR-3/4, BAFF, APRIL…

… j, Immunoprecipitates and total lysates from 293T cells after incubation of purified E protein
from SARS-CoV-2 with overexpressed human TLR2 or TLR3, or mouse TLR2. Student’s t-test …

… Severe acute respiratory syndrome coronavirus (SARS-CoV) … inflammatory cytokines in
Toll-like receptor 3 (TLR3) and retinoic … its antagonistic mechanism of SARS-CoV PLPro on TLR7-…

… model of SARS-CoV, we demonstrate the importance of TLR … that the TLR3 agonist
ARNAX, which directly targets TLR3 in … to sc vaccination with the SARS S protein. In addition, …