T Yamada, A Takaoka - Inflammation and Regeneration, 2023 - Springer
… with TLR3 and … SARS-CoV-2 infection in Calu-3/MRC-5 multicellular spheroids [58]. Further studies are needed to clarify what PAMPs are directly sensed by TLRs during SARS-CoV-2 …
MCS Menezes, ADM Veiga, T Martins de Lima… - Scientific reports, 2021 - nature.com
… This study explored the impact that SARS-CoV-2 infection could have in the peripheral blood … Here, we demonstrate that lower expression of TLR-3 and an enhanced expression of TLR-…
J Deng, Y Zheng, SN Zheng, ML Nan… - Journal of Medical …, 2023 - Wiley Online Library
… Viral dsRNA can be also recognized by endosomal Toll-likereceptor3 (TLR3), which can evoke an IFN response via recruitment of TRIF. In addition, the cytoplasmic dsDNA sensor …
… other TLRs in SARS-CoV-2 infection has not been as conclusively studied in vitro and in vivo. In the context of SARS-CoV, the TLR3 … to date have linked TLR3 with SARS-CoV-2 sensing …
… infected with severe acute respiratory syndrome (SARS)-CoV [10]. The adaptive immune response that occurs during CoV infection is well characterized [3,5], but our understanding of …
C Salaris, M Scarpa, M Elli, A Bertolini, S Guglielmetti… - Nutrients, 2021 - mdpi.com
… expression of toll-likereceptor3 (TLR3) and 7 (TLR7), which are pattern recognition receptors involved in sensing of RNA viruses (Figure 2B), and of interferon regulatory factor 3 (IRF3) …
… In this review, we highlight the components of cell-based recognition of SARS-CoV-2 … TLR signaling can also promote nuclear translocation of the transcription factors IRF-3 and …
SK Jeong, YK Heo, JH Jeong, SJ Ham, JS Yum… - Vaccines, 2021 - mdpi.com
… whether a combination of toll-likereceptor (TLR)1/2 and TLR3 agonists (L-pampo) can be a potent adjuvant for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subunit …