T Akaike - Reviews in medical virology, 2001 - Wiley Online Library
… of viralpathogenesis almost a decade ago we sought to identify eOH generation in influenza virus-… Therefore, we may expect such chemical mutagenesis in DNA viruses, bacteria and …
… about such genetic variants in viruses that infect humans and threaten … viral infection (particularly in the case of RNA viruses) could play a pivotal role in virus evolution, pathogenesis …
E Domingo, J Gomez - Virus research, 2007 - Elsevier
… viral evolution that can affect viralpathogenesis. Relevant evolutionary events include the generation of minority virus … to viral extinction through enhanced mutagenesis (virus entry into …
ML Gatza, C Chandhasin, RI Ducu… - … mutagenesis, 2005 - Wiley Online Library
… been explicitly linked to the expression of oncoproteins encoded by these viruses. This review discusses mechanisms utilized by these viral oncoproteins, Tax, HBx, and E6/E7, to …
JT Schiffer, M Aubert, ND Weber, E Mintzer… - Journal of …, 2012 - Am Soc Microbiol
… in certain plant-pathogenic species of Xanthomonas (… The role that this process plays in bacterial pathogenesis in … and repair ultimately lead to mutagenic NHEJ pathways. In the …
… of the virus either towards survival through selection of mutagen-… involving the mutagenesis of foot-and-mouth disease virus (… effect of R-mediated mutagenesis on the selection of FMDV …
E Domingo, C Escarmís, L Menéndez-Arias… - … and evolution of viruses, 2008 - Elsevier
… ” in this chapter, we summarize our current view on the mechanisms that underlie virus extinction through lethal mutagenesis based on experimental results, and the main challenges …
H Moreno, H Tejero, JC De la Torre, E Domingo… - PloS one, 2012 - journals.plos.org
… extinction mediated by enhanced mutation rates during viral … Viral load and virus fitness are known to influence virus extinction. … of several RNA viruses under enhanced mutagenesis. …
E Domingo, AI de Avila, I Gallego… - Pathogens and …, 2019 - academic.oup.com
… virus apply to viruses that follow a different replicative cycle; (iv) the recognition that viral fitness per se is relevant to viralpathogenesis and viral … impelled by the mutagenic activity but it …