Characterization of viral proteins encoded by the SARS-coronavirus genome

YJ Tan, SG Lim, W Hong - Antiviral research, 2005 - Elsevier
… on the SARS-CoV viral proteins: their expression, cellular localization and effects on cellular
functions. Expeditious research on SARS-CoV … used for the various viral proteins. In order to …

SARS-CoV-2 accessory proteins in viral pathogenesis: knowns and unknowns

N Redondo, S Zaldívar-López, JJ Garrido… - Frontiers in …, 2021 - frontiersin.org
viral SARS-CoV-2 pathogenesis in COVID-19. Accessory proteins in SARS-CoV-2 consist of
eleven viral proteins … current knowledge of SARS-CoV-2 accessory proteins is summarized …

Structure and function of major SARS-CoV-2 and SARS-CoV proteins

R Gorkhali, P Koirala, S Rijal… - … and biology insights, 2021 - journals.sagepub.com
… The sequencing revealed that the novel virus had most proteins homologous to SARS-CoV, …
(I) Finally, replicated RNA and other translated viral proteins assembled into a new virus. …

Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication

JA Pan, X Peng, Y Gao, Z Li, X Lu, Y Chen, M Ishaq… - PloS one, 2008 - journals.plos.org
… reporter system of SARS-CoV was established in … viral proteins on the viral replication and
transcription and found that the N protein played an important role at the early stage of SARS-…

SARS-CoV-2 mutations and their viral variants

B Cosar, ZY Karagulleoglu, S Unal, AT Ince… - Cytokine & growth factor …, 2022 - Elsevier
… Genomic and subgenomic RNA synthesis takes place in the synthesis of viral proteins. Then,
with the help of ribosomes, viral RNAs are transmitted and viral proteins are synthesized. 8. …

Structural genomics of SARS-CoV-2 indicates evolutionary conserved functional regions of viral proteins

S Srinivasan, H Cui, Z Gao, M Liu, S Lu, W Mkandawire… - Viruses, 2020 - mdpi.com
virus target the same proteins in human cells as the known coronaviruses? Most importantly,
can the currently developed SARS … first 3D roadmap of SARS-CoV-2 viral proteins and their …

Accessory proteins of SARS-CoV and other coronaviruses

DX Liu, TS Fung, KKL Chong, A Shukla, R Hilgenfeld - Antiviral research, 2014 - Elsevier
… This review makes an attempt to summarize the published knowledge on SARS-CoV accessory
proteins, with an emphasis on their involvement in virus–host interaction. The accessory …

Structural biology of SARS-CoV-2 and implications for therapeutic development

H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
… In this Review, we delineate the structural features of SARS-CoV-2 from the whole viral
particle to the individual viral proteins and discuss their functions as well as their potential as …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
SARS-CoV, belongs to the genus Sarbecovirus 6 . This virus encodes a set of structural
proteins (membrane protein, … internalized virus particles may facilitate spreading of SARS-CoV-2 …

SARS-CoV-2 viral proteins NSP1 and NSP13 inhibit interferon activation through distinct mechanisms

C Vazquez, SE Swanson, SG Negatu, M Dittmar… - PloS one, 2021 - journals.plos.org
… Here, we show that SARS-CoV-2 can block IRF3 and NF-κB activation early during virus
infection. We also identify that the SARS-CoV-2 viral proteins NSP1 and NSP13 can block …