The regulation of adipocyte growth in white adipose tissue

Q Li, KL Spalding - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Adipocytes can increase in volume up to a thousand-fold, storing excess calories as
triacylglycerol in large lipid droplets. The dramatic morphological changes required of …

[HTML][HTML] Adipose tissue plasticity from WAT to BAT and in between

YH Lee, EP Mottillo, JG Granneman - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Adipose tissue plays an essential role in regulating energy balance through its metabolic,
cellular and endocrine functions. Adipose tissue has been historically classified into …

The cell biology of fat expansion

JM Rutkowski, JH Stern, PE Scherer - Journal of Cell Biology, 2015 - rupress.org
Adipose tissue is a complex, multicellular organ that profoundly influences the function of
nearly all other organ systems through its diverse metabolite and adipokine secretome …

Adipogenesis and metabolic health

AL Ghaben, PE Scherer - Nature reviews Molecular cell biology, 2019 - nature.com
Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

Causes and mechanisms of adipocyte enlargement and adipose expansion

F Haczeyni, KS Bell‐Anderson, GC Farrell - Obesity reviews, 2018 - Wiley Online Library
Adipose tissue plays a significant role in whole body energy homeostasis. Obesity‐
associated diabetes, fatty liver and metabolic syndrome are closely linked to adipose stress …

Contribution of adipogenesis to healthy adipose tissue expansion in obesity

L Vishvanath, RK Gupta - The Journal of clinical …, 2019 - Am Soc Clin Investig
The manner in which white adipose tissue (WAT) expands and remodels directly impacts the
risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT …

Adipogenesis: cellular and molecular aspects

B Fève - Best Practice & Research Clinical Endocrinology & …, 2005 - Elsevier
Obesity and lipoatrophy are major risks for insulin resistance, non-insulin-dependent
diabetes and cardiovascular disease. In the past three decades, significant advances have …

Adipocyte differentiation: from fibroblast to endocrine cell

FM Gregoire - Experimental Biology and Medicine, 2001 - journals.sagepub.com
Recent advances regarding the biology of adipose tissue have demonstrated that white
adipose tissue (WAT) plays a central role in the regulation of energy balance and acts as a …

Adipose morphology and metabolic disease

P Tandon, R Wafer… - Journal of Experimental …, 2018 - journals.biologists.com
Adipose morphology is defined as the number and size distribution of adipocytes (fat cells)
within adipose tissue. Adipose tissue with fewer but larger adipocytes is said to have a …

Adipocyte and adipogenesis

AT Ali, WE Hochfeld, R Myburgh, MS Pepper - European journal of cell …, 2013 - Elsevier
Adipocytes are the main constituent of adipose tissue and are considered to be a corner
stone in the homeostatic control of whole body metabolism. Their primary function is to …