Human amnion favours tissue repair by inducing the M1‐to‐M2 switch and enhancing M2 macrophage features

M Magatti, E Vertua, S De Munari… - Journal of tissue …, 2017 - Wiley Online Library
Human amniotic mesenchymal cells (hAMTCs) possess interesting immunomodulatory
properties, making them attractive candidates for regenerative medicine applications …

Human amnion mesenchymal cells inhibit lipopolysaccharide-induced TNF-α and IL-1β production in THP-1 cells

J Shu, X He, L Zhang, H Li, P Wang, X Huang - Biological research, 2015 - Springer
Background Human amnion mesenchymal cells (hAMCs), isolated from the amniotic
membrane of human placenta, are a unique population of mesenchymal stem cells. Recent …

Therapeutic potential of amniotic fluid derived mesenchymal stem cells based on their differentiation capacity and immunomodulatory properties

CR Harrell, M Gazdic, C Fellabaum… - Current stem cell …, 2019 - ingentaconnect.com
Background: Amniotic Fluid Derived Mesenchymal Stem Cells (AF-MSCs) are adult,
fibroblast-like, self-renewable, multipotent stem cells. During the last decade, the therapeutic …

[PDF][PDF] Transplantation of human amnion mesenchymal cells attenuates the disease development in rats with collagen-induced arthritis

J Shu, L Pan, X Huang, P Wang, H Li… - Clin Exp …, 2015 - clinexprheumatol.org
Objective Human amnion mesenchymal cells (hAMCs), isolated from the amniotic
membrane of human placenta, are a unique population of mesenchymal stem cells (MSCs) …

B lymphocytes as targets of the immunomodulatory properties of human amniotic mesenchymal stromal cells

M Magatti, A Masserdotti, P Bonassi Signoroni… - Frontiers in …, 2020 - frontiersin.org
Mesenchymal stromal cells (MSC) from the amniotic membrane of human term placenta
(hAMSC), and the conditioned medium generated from their culture (CM-hAMSC) offer …

Is immune modulation the mechanism underlying the beneficial effects of amniotic cells and their derivatives in regenerative medicine?

AR Silini, M Magatti, A Cargnoni… - Cell …, 2017 - journals.sagepub.com
Regenerative medicine aims to repair and regenerate damaged cells, tissues, and organs in
order to restore function. Regeneration can be obtained either by cell replacement or by …

Amniotic membrane mesenchymal cells-derived factors skew T cell polarization toward Treg and downregulate Th1 and Th17 cells subsets

S Pianta, P Bonassi Signoroni, I Muradore… - Stem Cell Reviews and …, 2015 - Springer
We previously demonstrated that cells derived from the mesenchymal layer of the human
amniotic membrane (hAMSC) and their conditioned medium (CM-hAMSC) modulate …

Human placental mesenchymal stem cells (pMSCs) play a role as immune suppressive cells by shifting macrophage differentiation from inflammatory M1 to anti …

MH Abumaree, MA Al Jumah, B Kalionis… - Stem Cell Reviews and …, 2013 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have a therapeutic potential in tissue
repair because of capacity for multipotent differentiation and their ability to modulate the …

Amniotic membrane-derived stem cells: immunomodulatory properties and potential clinical application

CL Insausti, M Blanquer… - Stem Cells and …, 2014 - Taylor & Francis
Epithelial and mesenchymal cells isolated from the amniotic membrane (AM) possess stem
cell characteristics, differentiation potential toward lineages of different germ layers, and …

Amniotic mesenchymal tissue cells inhibit dendritic cell differentiation of peripheral blood and amnion resident monocytes

M Magatti, S De Munari, E Vertua… - Cell …, 2009 - journals.sagepub.com
Cells derived from the amniotic membranes of human term placenta have drawn much
interest for their characteristics of multipotency and low immunogenicity, supporting a variety …