Obesity is a growing health concern worldwide because of its contribution to metabolic
syndrome, type II diabetes, insulin resistance (IR), and numerous cancers. In obesity, white …

Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

White adipose tissue is not only a highly heterogeneous organ containing various cells,
such as adipocytes, adipose stem and progenitor cells, and immune cells, but also an …

Obesity has become a global health issue due to its high prevalence and associated
comorbidities including insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Obesity …

Adipocytes can increase in volume up to a thousand-fold, storing excess calories as
triacylglycerol in large lipid droplets. The dramatic morphological changes required of …

Adipose tissue regulates numerous physiological processes, and its dysfunction in obese
humans is associated with disrupted metabolic homeostasis, insulin resistance and type 2 …

Adipose tissue plays an essential role in regulating energy balance through its metabolic,
cellular and endocrine functions. Adipose tissue has been historically classified into …

This review focuses on adipose tissue biology and introduces the concept of adipose tissue
plasticity and expandability as key determinants of obesity-associated metabolic …

Obesity is one of the biggest public health concerns identified by an increase in adipose
tissue mass as a result of adipocyte hypertrophy and hyperplasia. Pertaining to the …

White adipose tissue (WAT) expands under physiological conditions via an increase in
adipocyte size (hypertrophy) and/or number (hyperplasia; adipogenesis), and the ability of …