Contribution of adipogenesis to healthy adipose tissue expansion in obesity

L Vishvanath, RK Gupta - The Journal of clinical …, 2019 - Am Soc Clin Investig
The manner in which white adipose tissue (WAT) expands and remodels directly impacts the
risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT …

Weighing in on adipocyte precursors

R Berry, E Jeffery, MS Rodeheffer - Cell metabolism, 2014 - cell.com
Obesity, defined as an excessive increase in white adipose tissue (WAT), is a global health
epidemic. In obesity, WAT expands by increased adipocyte size (hypertrophy) and number …

Adipose stem cells in obesity: challenges and opportunities

S Shin, AS El-Sabbagh, BE Lukas… - Bioscience …, 2020 - portlandpress.com
Adipose tissue, the storage of excessive energy in the body, secretes various proteins called
adipokines, which connect the body's nutritional status to the regulation of energy balance …

Adipose tissue expansion in obesity, health, and disease

U White - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
White adipose tissue (WAT) expands under physiological conditions via an increase in
adipocyte size (hypertrophy) and/or number (hyperplasia; adipogenesis), and the ability of …

Adipogenesis and metabolic health

AL Ghaben, PE Scherer - Nature reviews Molecular cell biology, 2019 - nature.com
Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

Depot-specific differences in adipogenic progenitor abundance and proliferative response to high-fat diet

AWB Joe, L Yi, Y Even, AW Vogl, FMV Rossi - Stem cells, 2009 - academic.oup.com
White adipose tissue (fat) is the primary organ for energy storage and its regulation has
serious implications on human health. Excess fat tissue causes significant morbidity, and …

Concise review: adipocyte origins: weighing the possibilities

SM Majka, Y Barak, DJ Klemm - Stem Cells, 2011 - academic.oup.com
Adipose tissue is the primary energy reservoir in the body and an important endocrine organ
that plays roles in energy homeostasis, feeding, insulin sensitivity, and inflammation. While it …

The cell biology of fat expansion

JM Rutkowski, JH Stern, PE Scherer - Journal of Cell Biology, 2015 - rupress.org
Adipose tissue is a complex, multicellular organ that profoundly influences the function of
nearly all other organ systems through its diverse metabolite and adipokine secretome …

Modeling adipogenesis: current and future perspective

HF Bahmad, R Daouk, J Azar, J Sapudom, JCM Teo… - Cells, 2020 - mdpi.com
Adipose tissue is contemplated as a dynamic organ that plays key roles in the human body.
Adipogenesis is the process by which adipocytes develop from adipose-derived stem cells …

[HTML][HTML] Adipose tissue plasticity from WAT to BAT and in between

YH Lee, EP Mottillo, JG Granneman - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Adipose tissue plays an essential role in regulating energy balance through its metabolic,
cellular and endocrine functions. Adipose tissue has been historically classified into …