Alternatively activated “M2” macrophages are believed to function during late stages of
wound healing, behaving in an anti-inflammatory manner to mediate the resolution of the …

Review on tissue repair and M1-like to M2a-like macrophages, exhibiting important
differences from in vitro phenotypes. Mp are crucial for tissue repair and regeneration but …

Tissue repair is largely regulated by diverse Mϕ populations whose functions are timing-and
context-dependent. The early phase of healing is dominated by pro-inflammatory Mϕs, also …

Summary T helper type 2 (Th2) cytokine-activated M2 macrophages contribute to
inflammation resolution and wound healing. This study shows that IL-4-primed …

Distinct anti-inflammatory macrophage (M2) subtypes, namely M2a and M2c, are reported to
modulate the tissue repair process tightly and chronologically by modulating fibroblast …

As a component of the innate immune system, macrophages play a crucial role in host
defense against a variety of microbes. Conventionally, macrophages have been classified …

Macrophages are the main components of inflammation during skin wound healing. They
are critical in wound closure and in excessive inflammation, resulting in defective healing …

Significance: Macrophages are invariably present and tightly regulate all phases of adult
wound healing, including inflammation, granulation tissue formation, and matrix deposition …

Macrophages play key roles in all phases of adult wound healing, which are inflammation,
proliferation, and remodeling. As wounds heal, the local macrophage population transitions …

Macrophages are key immune cells that respond to infections, and modulate
pathophysiological conditions such as wound healing. By possessing phagocytic activities …