ML Novak, TJ Koh - Journal of leukocyte biology, 2013 - academic.oup.com
Review on tissue repair and M1-like to M2a-like macrophages, exhibiting important differences from in vitro phenotypes. Mp are crucial for tissue repair and regeneration but …
Tissue repair is largely regulated by diverse Mϕ populations whose functions are timing-and context-dependent. The early phase of healing is dominated by pro-inflammatory Mϕs, also …
B Dang, Q Gao, L Zhang, J Zhang, H Cai, Y Zhu… - Cell reports, 2023 - cell.com
Summary T helper type 2 (Th2) cytokine-activated M2 macrophages contribute to inflammation resolution and wound healing. This study shows that IL-4-primed …
Distinct anti-inflammatory macrophage (M2) subtypes, namely M2a and M2c, are reported to modulate the tissue repair process tightly and chronologically by modulating fibroblast …
S Bhattacharya, A Aggarwal - Rheumatology international, 2019 - Springer
As a component of the innate immune system, macrophages play a crucial role in host defense against a variety of microbes. Conventionally, macrophages have been classified …
MP Rodero, SS Hodgson, B Hollier… - Journal of Investigative …, 2013 - Elsevier
Macrophages are the main components of inflammation during skin wound healing. They are critical in wound closure and in excessive inflammation, resulting in defective healing …
A Sindrilaru, K Scharffetter-Kochanek - Advances in wound care, 2013 - liebertpub.com
Significance: Macrophages are invariably present and tightly regulate all phases of adult wound healing, including inflammation, granulation tissue formation, and matrix deposition …
P Krzyszczyk, R Schloss, A Palmer… - Frontiers in …, 2018 - frontiersin.org
Macrophages play key roles in all phases of adult wound healing, which are inflammation, proliferation, and remodeling. As wounds heal, the local macrophage population transitions …
Macrophages are key immune cells that respond to infections, and modulate pathophysiological conditions such as wound healing. By possessing phagocytic activities …