… disparate ligands. Our results identify CD36-TLR4-TLR6 activation as a common molecular
mechanism by which atherogenic lipids and amyloid-β stimulate sterile inflammation and …

… Ligand-induced dimerization of TLRs promotes … In atherosclerosis, CD36–TLR4–TLR6
activation was identified as a … lipids and amyloid- stimulate sterile inflammation [11]. Deficiency …

… After cargo ligand recognition, CD36 induces the formation of a heteromeric complex that …
Thus, CD36 controls crucial steps in sterile inflammation, assembling a non-transcriptional …

… Toll-like receptors (TLRs) are type-I transmembrane proteins … To analyze the effect of TLR
ligands on CD36 expression, … specific ELISAs according to the manufacturer’s instructions. All …

… in vitro through ligation of the Toll-like receptors (TLRs). Thus, … that CD36-mediated uptake
of IAPP may promote intracellular … assembly and caspase-1 activation 51 , the identification of …

… ligand Pam3, the TLR2/6 ligand FSL-1, and the TLR4 ligand LPS (Figure 1) to examine the
role of CD36 in the inflammatory … exogenous ligands cannot enhance inflammatory signaling …

… themselves primarily through toll-like receptor 4 (TLR4) 4 . After … by cooperating with TLR4
in ligand recognition and triggering … to the manufacturer’s instructions. After nucleofection, si-…

… ligands for CD36 disrupt insulin signalling in adipocytes … CD36 has been shown to be
a co-receptor for Toll-like … OxLDL promotes CD36-dependent molecular and physiologic …

… receptor CD36, toll-like receptors (TLR), and natural antibodies, recognize common
oxidation-specific ligands and … Our identification of uPAR assembly with CD36 and TLR4 provides …

… Notably, the Toll-like receptors (TLRs) and CD36 are … according to the manufacturer’s
instructions. Briefly, the cytokine … harbor a mutation in the Toll-like receptor 4 gene Tlr4 Lps-d [21]. …