Early effects of elexacaftor-tezacaftor-ivacaftor therapy on magnetic resonance imaging in patients with cystic fibrosis and advanced lung disease

L Macconi, V Galici, M Di Maurizio, E Rossi… - Journal of Clinical …, 2022 - mdpi.com
… patients, evaluating the changes in chest magnetic resonance imaging (MRI) three months
after the start of elexacaftor/tezacaftor and ivacaftor therapy. MRI showed a drastic reduction …

Magnetic resonance imaging detects improvements of pulmonary and paranasal sinus abnormalities in response to elexacaftor/tezacaftor/ivacaftor therapy in adults …

L Wucherpfennig, SMF Triphan, S Wege… - Journal of Cystic …, 2022 - Elsevier
… However, its effects on structural and functional lung abnormalities and chronic … F508del
mutation after first initiation of Elexacaftor/Tezacaftor/Ivacaftor treatment. These improvements in …

Effects of elexacaftor/tezacaftor/ivacaftor therapy on lung clearance index and magnetic resonance imaging in patients with cystic fibrosis and one or two F508del …

SY Graeber, DM Renz, M Stahl… - American journal of …, 2022 - atsjournals.org
… -breath washout and magnetic resonance imaging to determine effects of ELX/… Magnetic
resonance imaging detects changes in structure and perfusion, and response to therapy in early

[HTML][HTML] Elexacaftor/tezacaftor/ivacaftor improves chronic rhinosinusitis detected by magnetic resonance imaging in children with cystic fibrosis on long-term therapy …

L Wucherpfennig, JKZ Becker, F Wuennemann… - Journal of Cystic …, 2024 - Elsevier
effect of elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) on CRS detected by MRI in children
with CF and at least one F508del mutation, and potential incremental effects … an early onset of …

Elexacaftor/tezacaftor/ivacaftor improves bronchial artery dilatation detected by magnetic resonance imaging in patients with cystic fibrosis

L Wucherpfennig, SMF Triphan, S Wege… - Annals of the …, 2023 - atsjournals.org
… detects changes in structure and perfusion, and response to therapy in earlyEffects of
elexacaftor/tezacaftor/ivacaftor therapy on lung clearance index and magnetic resonance imaging

Longitudinal evaluation of bronchial changes in cystic fibrosis patients undergoing elexacaftor/tezacaftor/ivacaftor therapy using lung MRI with ultrashort echo‐times

M David, I Benlala, S Bui, T Benkert… - … Resonance Imaging, 2024 - Wiley Online Library
… , the effect on … of elexacaftor/tezacaftor/ivacaftor treatment, and correlations between MRI
Bhalla score and forced expiratory volume in 1 second percentage predicted (FEV1%p) at first

Effects of elexacaftor/tezacaftor/ivacaftor therapy in children with cystic fibrosis–a comprehensive assessment using lung clearance index, spirometry, and functional …

C Streibel, CC Willers, O Pusterla, G Bauman… - Journal of cystic …, 2023 - Elsevier
resonance imaging (MRI) provides sensitive spatially resolved … MP-MRI: Matrix-Pencil
Magnetic Resonance Imaging; ELX/… This is the first study to show these effects on defect …

Structural changes in lung morphology detected by MRI after modulating therapy with elexacaftor/tezacaftor/ivacaftor in adolescent and adult patients with cystic …

V Fainardi, K Skenderaj, A Ciuni, G Milanese… - Respiratory …, 2023 - Elsevier
… exacerbations and lung structure by chest magnetic resonance imaging (MRI) were assessed.
Early effects of elexacaftor-tezacaftor-ivacaftor therapy on magnetic resonance imaging in …

Effect of CFTR modulator therapy with elexacaftor/tezacaftor/ivacaftor on pulmonary ventilation derived by 3D phase-resolved functional lung MRI in cystic fibrosis …

F Klimeš, A Voskrebenzev, M Gutberlet, M Speth… - European …, 2024 - Springer
… To our best knowledge, this is the first study to determine the effects of ETI therapy on …
GmbH, a company, which has interest in pulmonary magnetic resonance imaging methods. …

Impact of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Children with Cystic Fibrosis and One or Two …

M Stahl, M Dohna, SY Graeber… - The European …, 2024 - europepmc.org
elexacaftor/tezacaftor/ivacaftor (ETI) improves the lung clearance index (LCI) and abnormalities
in lung morphology detected by magnetic resonance imaging (… Our results support early