… genome-wide DNA methylationprofiling using Illumina beadchips that query 26,486 autosomal CpGs. Beta scores (percentage methylation; … predictive model of humanagingrates from …
N Jain, JL Li, L Tong, F Jasmine, MG Kibriya… - Epigenetics & …, 2024 - ncbi.nlm.nih.gov
… age-related expression quantitative trait methylation (age-… the association between age and genome-wide measures of … first selected age-associated CpG sites, false discovery rate (…
… human DNAm clocks and age indicators track cellular aging in primary cultured fibroblasts, and compare the rate of aging … DNA methylation was quantified for 866,736 CpG sites using …
… makes RRBS substantially more cost efficient than genome-wide bisulfite sequencing. The … higher genomic coverage at competitive cost. Methylation-specific digestion was excluded …
… Several studies on methylationquantitative trait loci (meQTL) have identified genetic … This was done by maximizing false positive rate minus sensitivity with a detection p-value cutoff of …
… In this study, genome-widemethylationprofiles of 128 blood … the accuracy of the quantified DNA methylation level can be … assess the rate of change in DNA methylation with age in this …
MT Bocker, I Hellwig, A Breiling… - Blood, The Journal …, 2011 - ashpublications.org
… from the same human samples, we obtained detailed methylationprofiles at distinct stages … that are methylated in CD34 + hematopoietic progenitor cells but show pronounced DNA …
I Florath, K Butterbach, H Müller… - Human molecular …, 2014 - academic.oup.com
… between methylation levels quantified by beta-value and age … Genome-wide DNA methylation status was measured using … simultaneous quantitative measurement of the methylation …
I Shchukina, J Bagaitkar, O Shpynov, E Loginicheva… - Nature aging, 2021 - nature.com
… We used the MethPipe pipeline 41 to perform a genome-wide comparison of the methylomes between the two groups, which yielded 1,160 DMRs (Fig. 3f and Supplementary Table 12). …