… We also treated PAR as a quantitative trait to perform a genome-wide association study (GWAS)
and to identify genetic variants (ie, single nucleotide polymorphisms, SNPs) significantly …

… age (early-onset CRC or EOCRC) is currently unknown. In this study, we investigated the
genome-wide DNA methylation … an elevated mitotic rate per given years of age in our EOCRC …

… intensities on a scanned image were quantified, corrected for background noise, and …
This suggests that our empirical rate of false positives is 6%. We used our threshold criteria …

… statistics for the distribution of number of probes/BOP in the 3 Classes are reported. (B)
Descriptive statistics for … informativeness on genome-wide DNA methylation profiles. Alternative …

… rate for those with higher Δ age . … Genome wide single nucleotide polymorphisms and
exome chip data are also available. DNA methylation measured in subjects at an average age of …

… , gallstones, arthritis, and resting heart rate (measured with the Dinamap 1846SX automated
… (25) estimated heritability to be 0.65 using genome-wide complex trait analysis. Li et al. (56) …

… of genome-wide DNAm trajectories across this age period is … in girls at birth but DNAm
in boys increased at a higher rate. … We looked up methylation quantitative trait loci in cis (cis …

… genome-wide studies of methylation in normal human … , and the misclassification error rate
for each sample type (Table 2… Bead arrays have a similar sensitivity as quantitative methylation…

… Hochberg False Discovery Rate (FDR) with significantly differential methylation defined at
corrected P … Age-associated gene expression in normal breast tissue mirrors qualitative age-at-…

… , the age at diagnosis was tested using two different age cutoffs… less methylation events
showed better survival rates than … ) as we do not assess methylation in a quantitative way. After in …