Age-associated decrease of type IIA/B human skeletal muscle fibers.

WS Lee, WH Cheung, L Qin, N Tang… - … and Related Research …, 2006 - journals.lww.com
Elderly individuals often fall because of poor muscle strength and reduced balancing ability
related to muscle aging. However, it is unclear whether changes in muscle fiber types
contribute to poor strength or imbalance. We studied age-associated changes in human
skeletal muscle fibers using muscle biopsy specimens taken from 65 male and female
Chinese patients aged 17-96 years. The muscle specimens were cryosectioned with
alkaline triphosphatase staining at pH 4.4, followed by image analysis. We analyzed …
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