Aging is the major predictor for developing multiple neurodegenerative diseases, including
Alzheimer's disease (AD) other dementias, and Parkinson's disease (PD). Senescent cells,
which can drive aging phenotypes, accumulate at etiological sites of many age-related
chronic diseases. These cells are resistant to apoptosis and can cause local and systemic
dysfunction. Decreasing senescent cell abundance using senolytic drugs, agents that
selectively target these cells, alleviates neurodegenerative diseases in preclinical models. In …