Cocoa powder triggers neuroprotective and preventive effects in a human Alzheimer's disease model by modulating BDNF signaling pathway

A Cimini, R Gentile, B D'Angelo… - Journal of cellular …, 2013 - Wiley Online Library
The molecular mechanisms linking Aβ to the onset of neurotoxicity are still largely unknown,
but several lines of evidence point to reactive oxygen species, which are produced even
under the effect of nanomolar concentrations of soluble Aβ‐oligomers. The consequent
oxidative stress is considered as the mediator of a cascade of degenerative events in many
neurological disorders. Epidemiological studies indicate that dietary habits and antioxidants
from diet can influence the incidence of neurodegenerative disorders such as Alzheimer's …

[PDF][PDF] Cocoa Powder Triggers Neuroprotective and Preventive Effects in a Human Alzheimer 0 s Disease Model by Modulating BDNF Signaling Pathway

L Cristiano, ML Avantaggiati, A Giordano… - Journal of Cellular …, 2013 - researchgate.net
The molecular mechanisms linking Ab to the onset of neurotoxicity are still largely unknown,
but several lines of evidence point to reactive oxygen species, which are produced even
under the effect of nanomolar concentrations of soluble Ab‐oligomers. The consequent
oxidative stress is considered as the mediator of a cascade of degenerative events in many
neurological disorders. Epidemiological studies indicate that dietary habits and antioxidants
from diet can influence the incidence of neurodegenerative disorders such as Alzheimer 0 s …
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