Dendrimers in gene delivery

C Dufès, IF Uchegbu, AG Schätzlein - Advanced drug delivery reviews, 2005 - Elsevier
… Rational development of such vectors requires the link to be made between dendrimer
of dendrimers in those aspects of synthetic vector development. Dendrimer-based transfection

Dendrimers in gene transfection

DG Shcharbin, B Klajnert, M Bryszewska - Biochemistry (Moscow), 2009 - Springer
… of genetic material transfection using dendrimers with different cell lines. It was shown that
protonated dendrimers in … Transfection efficiency was dependent on the dendrimer type in the …

Disulfide cross-linked low generation dendrimers with high gene transfection efficacy, low cytotoxicity, and low cost

H Liu, H Wang, W Yang, Y Cheng - Journal of the American …, 2012 - ACS Publications
… can minimize the damage of cationic gene transfection reagents to transfected cells. The …
dendrimer-based gene vectors with low cost, low cytotoxicity, and high gene transfection

Surface-engineered dendrimers in gene delivery

J Yang, Q Zhang, H Chang, Y Cheng - Chemical reviews, 2015 - ACS Publications
… PAMAM dendrimer shows maximal gene transfection among … dendrimers can achieve
efficient gene transfection at … reducing the cytotoxicity of dendrimers on the transfected cells. Due …

[HTML][HTML] Polyamidoamine dendrimers as gene delivery carriers in the inner ear: How to improve transfection efficiency

H Wang, HB Shi, SK Yin - Experimental and therapeutic …, 2011 - spandidos-publications.com
… to increase their targeting transfection efficiency, interactions of dendrimers with lipid …
dendrimers with high transfection efficiencies and minimal cytotoxicity may be effective in gene

Poly (amidoamine) dendrimer complexes as a platform for gene delivery

D Shcharbin, A Shakhbazau… - Expert opinion on drug …, 2013 - Taylor & Francis
… The appearance of these paradigms induced a burst of studies devoted to the application
of PAMAM dendrimers in gene transfection and their modification, with the aim of improving …

Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues

A Kumar, VK Yellepeddi, GE Davies… - International journal of …, 2010 - Elsevier
… prepare and to evaluate gene transfection efficiency and cytotoxicity of the ornithine-conjugated
PAMAMG4 dendrimers. Ornithine-conjugated PAMAMG4 dendrimers were prepared by …

Mechanism of gene transfection by polyamidoamine (PAMAM) dendrimers modified with ornithine residues

A Kumar, VK Yellepeddi, KK Vangara… - Journal of Drug …, 2011 - Taylor & Francis
dendrimers of different generations and their transfection efficiency was tested in HEK 293T
cells. As shown in Figure 3 , transfection … and G4 PAMAM dendrimers respectively, whereas, …

How to study dendriplexes II: Transfection and cytotoxicity

D Shcharbin, E Pedziwiatr, J Blasiak… - Journal of Controlled …, 2010 - Elsevier
… analyzing the transfection efficiencies and cytotoxicities of dendriplexes–complexes of nucleic
acids with dendrimers. Analysis shows that three plasmids are mainly used in transfection

Activated and non-activated PAMAM dendrimers for gene delivery in vitro and in vivo

G Navarro, CT de ILarduya - Nanomedicine: Nanotechnology, Biology and …, 2009 - Elsevier
… (PAMAM) dendrimers and plasmid DNA … dendrimers on activation after heat treatment has
been tested to attempt an enhancement in transfection activity over that of intact dendrimers. …