In order to overcome the effect of the Multiple Access Interference (MAI) and noises, and increase the number of the simultaneous users, the multiplexing capacity and data rate, this paper proposes a novel design of a two dimensional spectral/spatial code named Two Dimensional-Single Weight Zero Cross Correlation (2D-SWZCC) based on a single weight code which is characterized by a zero cross correlation and a high number of users. The proposed code is developed to be implemented in non-coherent Optical Code Division Multiple Access (OCDMA) systems. Numerical results of the design construction show that the proposed code enhances the system performance by improving its capacity, reducing the signal-to-noise ratio, and increasing the data rate. The system output performance for active user number is equal to 1.09, 1.54, 2.14, 2.215, 3.89 and 5.14 times than those of, Two Dimensional Multi-Diagonal (2D-MD), Two Dimensional Dynamic Cyclic Shift (2D-DCS), (1D-SWZCC), Two Dimension Perfect Difference (2D-PD), Two Dimensional Hybrid Flexible Cross Correlation- Modified Double Weight (FCC/MDW) and Two Dimensional Extended Enhanced Double Weight (2D-extended-EDW) codes, respectively. It can save an effective power around −3.2 dBm and −1.4 dBm at the level of the receiver compared to 2D-DCS and 2D-MD codes. Moreover, the system performance has been studied using Optisystem software. The simulation results show that the system respects the optical transmission property accommodating four users for a power of the source equal to −10 dBm, and the data rate is 1 Gbps.