[HTML][HTML] Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors

N Mullins, JE Kang, AI Campos, JRI Coleman… - Biological …, 2022 - Elsevier
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts,
which occur far more frequently, are a major source of disability and social and economic
burden. Both have substantial genetic etiology, which is partially shared and partially distinct
from that of related psychiatric disorders. Methods We conducted a genome-wide
association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the
International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on …
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