Epigenetic predictor of age

S Bocklandt, W Lin, ME Sehl, FJ Sánchez… - PloS one, 2011 - journals.plos.org
… estimate of predictive accuracy for age, we used … prediction was related to the truly observed
age of the left-out subject. The predicted values are highly correlated with the observed age

Epigenetic age prediction

DJ Simpson, T Chandra - Aging cell, 2021 - Wiley Online Library
Epigenetic clocks have proven themselves to be accurate at predicting chronological age
(chAge), which is commonly referred to as DNAm age or epigenetic age (eAge). When …

Epigenetic aging: Biological age prediction and informing a mechanistic theory of aging

A Li, Z Koch, T Ideker - Journal of internal medicine, 2022 - Wiley Online Library
… Here, we outline emerging areas of epigenetic aging research that prioritize biological …
progress in epigenetic clocks, which are beginning to predict not only chronological age but aging …

The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis

PD Fransquet, J Wrigglesworth, RL Woods, ME Ernst… - … epigenetics, 2019 - Springer
Epigenetic mechanisms may play a role in human ageing, and DNA methylation age
biomarkers may be good predictors of age-related diseases and mortality risk. The aims of this …

Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort

L Perna, Y Zhang, U Mons, B Holleczek, KU Saum… - … epigenetics, 2016 - Springer
… Our findings revealing that epigenetic age acceleration was also associated with a 20 %
greater CVD mortality risk (for estimates based on Horvath’s predictor) reveal a magnitude of …

[HTML][HTML] Epigenetic-aging-signature to determine age in different tissues

CM Koch, W Wagner - Aging (Albany NY), 2011 - ncbi.nlm.nih.gov
… Notably, the epigenetic age predictor for saliva samples by Bocklandt and co-workers also
included the CpG site corresponding to NPTX2 [22] and TRIM58 as well as GRIA2 were also …

Refining epigenetic prediction of chronological and biological age

E Bernabeu, DL McCartney, DA Gadd, RF Hillary… - Genome Medicine, 2023 - Springer
… (cAge) and biological age (bAge). The latter is typically defined by … Here, we aim to develop
accurate epigenetic predictors of … Finally, we refined epigenetic prediction of both cAge and …

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

Q Zhang, CL Vallerga, RM Walker, T Lin, AK Henders… - Genome medicine, 2019 - Springer
… This study indicates that the epigenetic clock can be improved by … attenuates with increased
prediction of chronological age. … of our age predictors: (1) correlation between predicted age

Analysis of epigenetic age predictors in pain-related conditions

KM Kwiatkowska, MG Bacalini, C Sala… - Frontiers in Public …, 2020 - frontiersin.org
… the Horvath's epigenetic age calculator to obtain DNAm-based estimates of epigenetic age,
… We did not find differences in epigenetic age acceleration, calculated using five different …

Association of facial ageing with DNA methylation and epigenetic age predictions

RE Marioni, DW Belsky, IJ Deary, W Wagner - Clinical Epigenetics, 2018 - Springer
… the hypothesis that an epigenetic predictor for biological age might be trained on face-age
as a surrogate for biological age rather than on chronological age. Our data demonstrate that …