… all the publicly available data, we derived the xMHC gene map that is reported here and
we discuss it in the context of the main hallmarks of MHC biology and disease. Gene map …

… In the long term, the biological importance of the MHC is likely to justify the re-sequencing
and epigenetic analysis of several common haplotypes, which differ markedly in sequence …

… In conclusion, we have created a dense haplotype map across the extended MHC in four
population samples. This resource will facilitate the selection of informative tag SNPs to …

… Recently, the human MHC was expanded to cover 7.6 Mb because the surrounding … to the
mouse MHC, contain MHC-similar genes and display LD that extends past the original MHC …

… gene maps of other mammals and vertebrates do not cTAN1 by FISH and the cosmid localized
to human … the mechanisms of chroparalogous genes mapping to the three chromosomes, …

… genes produced more than 1 MAP (Figure 1B). To estimate the diversity of a multiallelic
immunopeptidome, we computed the size of the MAP repertoire and MAP source gene … extend …

… ; inter-gene sequence homologies; structural variation; and long-… the accessibility of genetic
variation in the MHC; these … ; (iii) long-read-based diploid de novo assembly of the MHC; (…

… MHC from large-insert cloned DNA provides a definitive resource for the construction of
informative genetic maps, … between BACs that represent the extended MHC class I region. These …

… We next extended the contigs using paired-end information and a ‘greedy algorithm.’ If a
contig was at least 1 kbp long, we found all read-pairs for which one read aligns perfectly to a …

… Also, during the long period of serological HLA typing, class I has heen typed … genetic map
of the MHC hecomes available. The first observation of Id between genes in the human MHC …