The advent of genome-wide association studies for bacteria

PE Chen, BJ Shapiro - Current opinion in microbiology, 2015 - Elsevier
… Significant advances in sequencing technologies and genome-wide association studies (GWAS)
have revealed substantial insight into the genetic architecture of human phenotypes. In …

Meta-analysis of genome-wide association studies for personality

MHM De Moor, PT Costa, A Terracciano… - Molecular …, 2012 - nature.com
… Here we report on a meta-analysis of genome-wide association (GWA) data for personality
in 10 discovery samples (17 375 adults) and five in silico replication samples (3294 adults). …

Genome-wide association studies of obesity and metabolic syndrome

T Fall, E Ingelsson - Molecular and cellular endocrinology, 2014 - Elsevier
… , we aimed to include all original genome-wide association studies, including meta-analyses
of … search terms: (“Genome-Wide Association Study” [Mesh] OR “genome-wide” OR “whole-…

Genome-wide association studies for common diseases and complex traits

JN Hirschhorn, MJ Daly - Nature reviews genetics, 2005 - nature.com
… , which include both LINKAGE MAPPING and genome-wide association studies. The main
… present arguments as to why genome-wide association studies might be advantageous for …

Prediction of individual genetic risk to disease from genome-wide association studies

NR Wray, ME Goddard, PM Visscher - Genome research, 2007 - genome.cshlp.org
… in the association study could be useful to create genome-wide … of risk prediction from
genome-wide association studies and to … on a simulated genome-wide association study (GWAS). …

Successful design and conduct of genome-wide association studies

CI Amos - Human molecular genetics, 2007 - academic.oup.com
Genome-wide association studies are becoming an increasingly effective tool for identifying
… In this review, I discuss two sets of genome-wide association studies that identified novel …

A decade of genome-wide association studies for coronary artery disease: the challenges ahead

J Erdmann, T Kessler, L Munoz Venegas… - Cardiovascular …, 2018 - academic.oup.com
… The discoveries began with individual studies using 200K … on the findings of genome-wide
association studies. Moreover, … be enhanced by genome-wide association study findings in …

GWASTools: an R/Bioconductor package for quality control and analysis of genome-wide association studies

SM Gogarten, T Bhangale, MP Conomos… - …, 2012 - academic.oup.com
… to make genome-wide association studies (GWAS) an attractive option for many investigators.
The success of GWAS depends in large part on rigorous quality control (QC) and quality …

An overview of genome-wide association studies

M Chang, L He, L Cai - Computational Systems Biology: Methods and …, 2018 - Springer
… of statistical methods for genome-wide association studies. Here we describe how to perform
basic statistical analysis in a population-based genetic association case-control study. The …

Methods for investigating gene-environment interactions in candidate pathway and genome-wide association studies

D Thomas - Annual review of public health, 2010 - annualreviews.org
Despite the considerable enthusiasm about the yield of novel and replicated discoveries of
genetic associations from the new generation of genome-wide association studies (GWAS), …