Practical aspects of imputation-driven meta-analysis of genome-wide association studies

PIW De Bakker, MAR Ferreira, X Jia… - Human molecular …, 2008 - academic.oup.com
… Motivated by the overwhelming success of genome-wide association studies, droves of
researchers are working vigorously to exchange and to combine genetic data to expediently …

Genome-wide association studies in Alzheimer's disease: a review

G Tosto, C Reitz - Current neurology and neuroscience reports, 2013 - Springer
… of common variants through genome-wide association studies. The identification of several
… Ongoing and future large-scale genome-wide association studies, translational studies, and …

Genome-wide association studies of allergic diseases

M Tamari, S Tanaka, T Hirota - Allergology International, 2013 - jstage.jst.go.jp
… pathways underlying them, a large number of genetic studies have been conducted. Progress
in genetics enables us to conduct genome-wide association studies (GWASs), which is a …

GWASdb: a database for human genetic variants identified by genome-wide association studies

MJ Li, P Wang, X Liu, EL Lim, Z Wang… - Nucleic acids …, 2012 - academic.oup.com
… traits and diseases have been identified by genome-wide association studies (GWAS). The
genome-wide variation on a much larger scale. With increasing sample sizes, GWAS studies

Genome-wide association studies in diverse populations

NA Rosenberg, L Huang, EM Jewett… - Nature Reviews …, 2010 - nature.com
Genome-wide association (GWA) studies have identified a large number of SNPs associated
with disease phenotypes. As most GWA studies … consideration of GWA studies to diverse …

Avoiding the high Bonferroni penalty in genomewide association studies

X Gao, LC Becker, DM Becker… - … Official Publication of …, 2010 - Wiley Online Library
… testing adjustment in genetic association studies. However, it … to be promising in genetic
association studies. In this study, we … We also show that Meff is indeed valid on a genome-wide

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

AD Skol, LJ Scott, GR Abecasis, M Boehnke - Nature genetics, 2006 - nature.com
… We recommend joint analysis for all two-stage genome-wide association studies, especially
when a relatively large proportion of the samples are genotyped in stage 1 (π samples ≥ …

Interpretation of risk loci from genome-wide association studies of Alzheimer's disease

SJ Andrews, B Fulton-Howard, A Goate - The Lancet Neurology, 2020 - thelancet.com
… the causal gene in known loci identified in genome-wide association studies. Rare genetic
variant analyses in Alzheimer's disease have identified coding variants located within PLD3, …

easyGWAS: a cloud-based platform for comparing the results of genome-wide association studies

DG Grimm, D Roqueiro, PA Salomé… - The Plant …, 2017 - academic.oup.com
genome-wide association studies (GWAS). The systematic comparison of results obtained
from GWAS of different traits opens up new possibilities, including the analysis of pleiotropic …

[HTML][HTML] Genome-wide association studies of brain imaging phenotypes in UK Biobank

LT Elliott, K Sharp, F Alfaro-Almagro, S Shi, KL Miller… - Nature, 2018 - nature.com
… To investigate this, we carried out genome-wide association studies of 3,144 functional and
… We identify 148 clusters of associations between single nucleotide polymorphisms and …