High-density mapping of the MHC identifies a shared role for HLA-DRB1 (star) 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
C HAWKEY, C Abraham, P Goyette… - Nature … - nottingham-repository.worktribe.com
Genome-wide association studies of the related chronic inflammatory bowel diseases (IBD)
known as Crohn's disease and ulcerative colitis have shown strong evidence of association
to the major histocompatibility complex (MHC). This region encodes a large number of
immunological candidates, including the antigen-presenting classical human leukocyte
antigen (HLA) molecules1. Studies in IBD have indicated that multiple independent
associations exist at HLA and non-HLA genes, but they have lacked the statistical power to …
known as Crohn's disease and ulcerative colitis have shown strong evidence of association
to the major histocompatibility complex (MHC). This region encodes a large number of
immunological candidates, including the antigen-presenting classical human leukocyte
antigen (HLA) molecules1. Studies in IBD have indicated that multiple independent
associations exist at HLA and non-HLA genes, but they have lacked the statistical power to …
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
P Goyette, G Boucher, D Mallon, E Ellinghaus… - Nature …, 2015 - nature.com
Genome-wide association studies of the related chronic inflammatory bowel diseases (IBD)
known as Crohn's disease and ulcerative colitis have shown strong evidence of association
to the major histocompatibility complex (MHC). This region encodes a large number of
immunological candidates, including the antigen-presenting classical human leukocyte
antigen (HLA) molecules. Studies in IBD have indicated that multiple independent
associations exist at HLA and non-HLA genes, but they have lacked the statistical power to …
known as Crohn's disease and ulcerative colitis have shown strong evidence of association
to the major histocompatibility complex (MHC). This region encodes a large number of
immunological candidates, including the antigen-presenting classical human leukocyte
antigen (HLA) molecules. Studies in IBD have indicated that multiple independent
associations exist at HLA and non-HLA genes, but they have lacked the statistical power to …
以上显示的是最相近的搜索结果。 查看全部搜索结果