The purpose of the monograph is to develop theoretical and methodological provisions and methodological tools for increasing the innovative activity of entrepreneurship subjects in industry on the basis of a system-integration management model. The following tasks are solved in the work: the essence, classification of innovations, innovation process and innovation policy, innovation system are investigated; a theoretical model of innovative development of industrial enterprises is developed; the stages of the process of industrial innovation are determined; comparative organizational and economic characteristics of the activities of domestic and foreign corporations are selected and formulated, determining the innovative potential and the basic requirements for efficiency and financial stability; the international experience of innovation and the possibilities of its use at enterprises of Uzbekistan are analyzed. The book is of interest to students, applicants for scientific degrees, scientists, business leaders and anyone interested in the problems of innovation management. Keywords: innovation, innovative activity, industry, business entities, economy of Uzbekistan.